Protein Alignment CG14744 and Slc24a2

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: XP_006538405.1
• Gene: Slc24a2 / 76376
• MGIID: 1923626
• Length: 746
• Species: Mus musculus
• Alignment Length: 637
• Identity: 120/637 - (18%)
• Similarity: 237/637 - (37%)
• Gaps: 154/637 - (24%)

  Fly    79 LLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV---R 140
            :::.||.:|.:      ...:|.|.|.:|:.||.:::.:||.||:|.|..:||:..:|:.|   .
Mouse   143 MIYMFIALAIV------CDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAH 201

  Fly   141 ADAPIFTITVGNTLAIILLSGGTVCFLRP-FRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAVTLG 204
            ::..|.||.......|:.:.|....|.|. ..:......||:.|.::.:.:| .....:..:...
Mouse   202 SNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLLML-ITFFLDNVIMWW 265

  Fly   205 EGIVLFLIYVVYVAINIADLALLRYYIRKLRRELDYLEGLTPPPITEINAKIRKLISWEEQDDIG 269
            |.::|...|..||.....::.:.|:..:.:.|     ..:....:.|..||:.:.....:.|...
Mouse   266 ESLLLLTAYFAYVVFMKFNVQVERWVKQMISR-----NNVIKVTVPEAQAKLSEFPPASQADGRT 325

  Fly   270 IKDTTK---------YRRSRDTGNHFSNMTS-SGYFVTPIPERRSEHVDYELNRTALHDSENP-- 322
            ...|..         :....:|..|.|.:|: :|   .|:.| ::::...|.:.|| .|.:.|
Mouse   326 ACPTITNDPDCQSLCFEVYPETARHGSCITNVNG---EPLKE-KTQNSCMEESPTA-GDKDGPTL 385

  Fly   323 ---------------------------------KNLQLFTEFFQ-SLNPVDAEAWQLGGW----- 348
                                             .|..:....|| .::.:|..|.:||.:
Mouse   386 PVGSSSAACSCTSEECVAESKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKY 450

  Fly   349 -------------SNRIYLIA--RCPLVFVLQLFIPVVDYEKIKHGWSKLLNCTQIVTNPFVVIT 398
                         ::.::.||  :|.           ||..:.::|.:..:...::..:....:.
Mouse   451 YDTMTEEGRFREKASILHKIAKKKCQ-----------VDENERQNGAANHVEKIELPNSTSTEVE 504

  Fly   399 LVHSGVSS-------------------VYKTWHITLDFSISMWSP---------CLTVPLAIVIF 435
            :..|..:|                   ..:|.....|..:|:..|         .:..|:...::
Mouse   505 MTPSSEASEPVQNGNLSHNIEAADAPKATETAEEEDDQPLSLSWPTNTRKQATFLIVFPIVFPLW 569

  Fly   436 LHSRTDVPPSYHHLFIILTFFSSMVTLWLAVTELEVL--SEIVGIVFNLSESFMAVTFEAVSNAT 498
            : :..||.......|..:|||.|:.  |:||....::  :..||....:||..|.:|..|...:.
Mouse   570 I-TLPDVRKPASRKFFPITFFGSIT--WIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSI 631

  Fly   499 PDIIANYQLALQGYGRMAFAAIIGGPVFAILVSMSLAFIFN---HRVREVGANSWVYGDLGDNC- 559
            ||:|.:..:|.:|.|.||.::.:|..:|.|.|.:.|.::..   ||...|..:|     .|..|
Mouse   632 PDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTIIHRFSPVTVSS-----NGLFCA 691

  Fly   560 -------YLFLVITIVTTMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVE 604
                   .||::::|....|       ...:..|..::.:|..||:.:|.:|
Mouse   692 IVLLFIMLLFVILSIALCKW-------RMNKILGFIMFGLYFVFLVVSVLLE 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	35/145 (24%)
		Na_Ca_ex	450..601	CDD:279963	42/163 (26%)
Slc24a2	XP_006538405.1	2A1904	<99..746	CDD:273344	120/637 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810