Protein Alignment CG14744 and slc24a6a

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: XP_009289475.1
• Gene: slc24a6a / 561209
• ZFINID: ZDB-GENE-100922-39
• Length: 639
• Species: Danio rerio
• Alignment Length: 625
• Identity: 138/625 - (22%)
• Similarity: 227/625 - (36%)
• Gaps: 192/625 - (30%)

  Fly    78 MLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV--- 139
            :||..|..|...:.::.....:|.|.|:.|...||::|.:||.||:|.|:.:||:..:|:.|
Zfish   107 ILLHVFCAVYMFYALAIVCDVFFVPSLEKICENLHLSEDVAGATFMAAGSSAPELFTSLIGVFIT 171

  Fly   140 RADAPIFTI---TVGNTLAII----LLSGGTVCFLRPFRMNGHSTLRDLLFLLLGVEVLRFVMIK 197
            :.|..:.||   .|.|.|.||    :.:|.|:      .:......||.:|.:|.|..| .::|.
Zfish   172 KGDLGVGTIVGSAVFNILVIIGVCGIFAGQTI------TLTWWPLFRDSIFYILSVLAL-ILIIY 229

  Fly   198 EGAVTLGEGIVLFLIYVVYVAI-----NIADLALLRY-------YIRKLRRE------------- 237
            :..|...|.|:|..:|.||:.|     .|......|:       .:..|||:
Zfish   230 DEKVIWWETIILISMYGVYILIMKFNSQIWGWVEQRFGIPGQPCLVSSLRRDVSVGEASPHCDTS 294

  Fly   238 -------------------LDYLEGLTPPPITEINAKIRKLIS--WEEQDDIG------IKDTTK 275
                               :|.|..|.|...:...|.:|.:|:  :..:..:.      |.:..:
Zfish   295 MILLKKGQNAGGQDSPVVMVDELMSLHPHQFSFSEASLRVMITPHFSPRTRLSMAGRMLITERQR 359

  Fly   276 YRRSRDTGNHFSNMTSSGYFVTP----------------------------IPERRSEHVDYELN 312
            ..|:|..|    :.:.||...||                            .|.|||:  ..||.
Zfish   360 LIRNRSPG----DSSGSGAGDTPGQDGPGMEAVPWGLENGGALESETQPLEEPRRRSQ--GGELE 418

  Fly   313 RTALHDSENPKNLQLFTEFFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIK 377
            |.|..:...||:.:      :.....|.|.::              |..      :|...:|:.|
Zfish   419 RVADIEDTQPKDDE------EDEEEADEEPFR--------------PFT------VPEGRWEQAK 457

  Fly   378 HGWSKLLNCTQIVTNPFVVITLVHSGVSSVYKTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDV 442
            ..:|..|:|....|.|..|:
Zfish   458 WMFSWPLSCLLYYTVPNCVL--------------------------------------------- 477

  Fly   443 PPSYHHLFIILTFFSSMVTLWLAV-TELEV-LSEIVGIVFNLSESFMAVTFEAVSNATPDIIANY 505
             |.:...|:: ||.:|  |||:|| :.|.| :..|:....::.:..|.:||.|...:.||.:|:.
Zfish   478 -PRWERWFMV-TFVAS--TLWIAVFSYLMVWMVTIISFTLDIPDVVMGITFLAAGTSVPDCMASL 538

  Fly   506 QLALQGYGRMAFAAIIGGPVFAILVSMSLAFIFNHRVREVGA----NS--WVYGDLGDNCYLFLV 564
            .:|.||.|.||.:..||..:|.||:.:...:.....|.:.|:    ||  .||..:.....:||.
Zfish   539 IVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLVVDYGSTVSINSKGLVYSVILLLASVFLT 603

  Fly   565 ITIVTTMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVE 604
            :..|....|.:.      |..|:.|..:|..|||.::|.|
Zfish   604 VLSVHLNHWRLD------RRLGLGLMFLYAIFLLCSICFE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	46/156 (29%)
		Na_Ca_ex	450..601	CDD:279963	47/158 (30%)
slc24a6a	XP_009289475.1	Na_Ca_ex	<85..637	CDD:332332	137/623 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810