DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14744 and slc8b1

DIOPT Version :9

Sequence 1:	NP_001097232.2	Gene:	CG14744 / 35858	FlyBaseID:	FBgn0033324	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_021333605.1	Gene:	slc8b1 / 560601	ZFINID:	ZDB-GENE-130530-900	Length:	301	Species:	Danio rerio

Alignment Length:	222	Identity:	56/222 - (25%)
Similarity:	96/222 - (43%)	Gaps:	19/222 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KNMSCRAVMRLPYNYRCRMATQVSDCKRIINFFNYFRMMYCSID---IDDKATEVLFMLLFAFIC 85
            |...|..||.:..:.||.......||.....|..|..:.:|...   :....|..:..|||.|:.
Zfish    51 KGDECDVVMNVSASQRCEYVKNTPDCASDEGFIKYPFVTFCLFTPSLLPLAITIYVIWLLFLFLV 115

  Fly    86 VAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLM----PVRADAPIF 146
            :..:      ...:|.|.|..|:..|.:...:|||||||.||.:|::.:.:.    |..|...|.
Zfish   116 LGLI------ASDFFCPNLSAIASTLRLTHNVAGVTFLALGNGAPDVFSAMAAFSHPQTAGLAIG 174

  Fly   147 TITVGNTLAIILLSGGTVCFLRPFRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAVTLGEGIVLFL 211
            .: .|..:.:..:..|:|..::||.:.....|||::|.:..| ...|.::.:|.::|||.:....
Zfish   175 AL-FGAGIFVTTVVAGSVALVKPFTVASRPFLRDVIFYMAAV-FWTFTVLYKGHISLGESVGYLG 237

  Fly   212 IYVVYVAINIADLALLRYYIRKLRREL 238
            :|:.||...|    |..|...:.:.:|
Zfish   238 MYIAYVFTVI----LSSYIYNRQKHQL 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	40/145 (28%)
CG14744	NP_001097232.2	Na_Ca_ex	450..601	CDD:279963
slc8b1	XP_021333605.1	Na_Ca_ex	66..>246	CDD:332332	48/187 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581762
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41602
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		otm26516
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.750