Protein Alignment CG14744 and CG12376

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 205/613 - (33%)
• Similarity: 340/613 - (55%)
• Gaps: 32/613 - (5%)

  Fly    16 DHEFHYFIKNMSCRAVMRLPYNYRCRMATQVSDCKRIINFFNYFRMMYCSIDIDDKATEVLFMLL 80
            |.||..|...:||.|....|:..||.......||.|..|...|.|:|.|.::..::..:|:|:.|
  Fly    13 DAEFDNFWDTVSCYAANTFPFEERCAFVASAKDCNRSTNVLPYMRIMACDLNCVNEFEQVIFLAL 77

  Fly    81 FAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPVRADAPI 145
            |..:|...|.|:......|:||.||.:|..|.|||::||||.|||||.|.::.:||..|.|:.|:
  Fly    78 FMGLCYEILVLLIHVCNKYYSPALKAVSRFLCMNEHVAGVTLLAFGNSSADLFSNLASVNANVPV 142

  Fly   146 FTITVGNTLAIILLSGGTVCFLRPFRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAVTLGEGIVLF 210
            |..::...|.:.::|||.:|:..||:||.:.::||:|||:.|..:|::.:.....|.....||:|
  Fly   143 FANSLAAALFVSMVSGGLICYTSPFKMNAYESVRDILFLIFGSMLLQYFLASSAHVPETSFIVMF 207

  Fly   211 LIYVVYVAINIADLALLRYYIRKLRRELDYLEGLTPPPITEINAKIRKLISWEEQDDIGIKDTTK 275
            |:|:.|:.:|:.|:.|:|..::....::|.|      .:.|:..:.||.:|..|      ::...
  Fly   208 LVYIFYILVNVVDVYLIRRALKTTNAQIDAL------LVGEMTPEKRKRLSELE------RNQAI 260

  Fly   276 YRRSRDTGNHFSNMTSSGYFV-----TPIPERRSEHV--DYELNRTALHDSENPKNLQLFTEFFQ 333
            |  :||........|:||..:     |.:...||..:  |.:..|..||:....:|..||.:.|.
  Fly   261 Y--TRDMEVEIFERTNSGPNINKIRYTTLRMGRSTRISLDRKATRMVLHNRALGRNWGLFKDLFI 323

  Fly   334 SLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHGWSKLLNCTQIVTNPFVVIT 398
            :|.|::.|.|:.|....|.:::.:.|.|.:..::||:||||..||||:|||||.|::.||.:.|.
  Fly   324 ALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKHGWNKLLNCIQVMLNPAMSIM 388

  Fly   399 LVHSGVSSVYKT-WHITL--DFSISMWSPCLTVPLAIVIFLHSRTDVPPSYHHLFIILTFFSSMV 460
            .:.:.:||...: |::.:  :...:|:|..:|||:|:.:|:.|||||||.||.:|.::....||.
  Fly   389 AIKALLSSRGNSLWYVAMGEEAIYAMYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMF 453

  Fly   461 TLWLAVTELEVLSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGPV 525
            .:::..||::.:.|::|.:..:.:.||..|.:|.:.:...:|||..:||.||.|||:|:.||||.
  Fly   454 MIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPF 518

  Fly   526 FAILVSMSLAF----IFNHRVREVGANSWVYGDLGDNCYLFLVITIVTTMWWSVTFDFHARRSAG 586
            |.:::|.|...    :|...|.|....    |:.|.|.::||.:.:.:|:.||.|..|.||||.|
  Fly   519 FTVVMSASTVMHVKNLFGLPVSEANQT----GNYGLNAFIFLNLGVFSTLLWSTTLGFFARRSVG 579

  Fly   587 VFLWLVYLQFLLYAVCVEWDVVHEFSRD 614
            :|..:.|..:||:|:.:...|:|.||.|
  Fly   580 IFSIVFYCIYLLFAILIHRKVIHSFSVD 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	54/141 (38%)
		Na_Ca_ex	450..601	CDD:279963	51/154 (33%)
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	190/576 (33%)
		Na_Ca_ex	85..219	CDD:279963	52/133 (39%)
		Na_Ca_ex	448..595	CDD:279963	51/150 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450097
Domainoid	1	1.000	91	1.000	Domainoid score	I14182
eggNOG	1	0.900	-	-		E1_COG0530
Homologene	1	1.000	-	-		H41602
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1872
Isobase	1	0.950	-	0	Normalized mean entropy	S4675
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		otm26516
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	P	PTHR12266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	1	1.000	-	-		X612
	15	14.790