Protein Alignment CG14744 and Slc24a5

DIOPT Version :10

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_778199.2
• Gene: Slc24a5 / 317750
• MGIID: 2677271
• Length: 501
• Species: Mus musculus
• Alignment Length: 561
• Identity: 127/561 - (22%)
• Similarity: 209/561 - (37%)
• Gaps: 166/561 - (29%)

  Fly    75 VLFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV 139
            |::.|:..::|:|    :|.....||.|.|:|||..|.:::.:||.||:|.|:.:||::...:.|
Mouse    70 VIYFLIILYMCMA----ISIVCDKYFLPSLEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGV 130

  Fly   140 ---RADAPIFTITVGNTLAIILLSGGTVCFLRPFRMNGHSTL------RDLLFLLLGVEVLRFVM 195
               :.|..|.|| :|:  ||..|.|  :|.......|..|||      ||.....:.|..: |.:
Mouse   131 FITKGDIGISTI-LGS--AIYNLLG--ICAACGLLSNMVSTLSCWPLFRDCAVYAVSVGAV-FGI 189

  Fly   196 IKEGAVTLGEGIVLFLIYVVYVAINIADLALLRYYIRK-------LRRELDYLEGLTPPPITEIN 253
            |.:..:...||..|.|||.:||.:...|..:.|:.::.       |.|.:            |..
Mouse   190 IFDNRIYWYEGAGLLLIYGLYVLLLCFDTTISRHVMKTCSPCCPCLARAM------------EER 242

  Fly   254 AKIRKLISWEEQDDIGIKDTTKYRRSRDTGNHFSNMTSSGYFVTPIPERRSEHVDYELNRTALHD 318
            .:.:.|:.||::..:.|:     |:||         |.||.|        .|...|.....:||.
Mouse   243 IEQQTLLGWEDESQLFIR-----RQSR---------TDSGIF--------QEDSGYSQLSLSLHG 285

  Fly   319 ----SENPKNLQLFTEFFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHG 379
                ||:|                                    |.||.:    |..|..:|  .
Mouse   286 LSQVSEDP------------------------------------PSVFSM----PEADLRRI--F 308

  Fly   380 WSKLLNCTQIVTNPFVVITLVHSGVSSVYKTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDVPP 444
            |        :::.|  :|||:                        .||.|           |...
Mouse   309 W--------VLSLP--IITLL------------------------ALTTP-----------DCRR 328

  Fly   445 SYHHLFIILTFFSSMVTLWL-AVTELEV-LSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQL 507
            .:...:.::|||  |..||: |.|.:.| :..:.|....:.::.|.:|..|...:.||.:.:..:
Mouse   329 KFWKNYFVITFF--MSALWISAFTYILVWMVTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLV 391

  Fly   508 ALQGYGRMAFAAIIGGPVFAILV-----SMSLAFIFNHRVREVGANSWVYGDLGDNCYLFLVITI 567
            |.:|.|.||.:.|:|..||.:|.     .:..||.......||.:....|..:..|..:..:...
Mouse   392 ARKGKGDMAISNIVGSNVFDMLCLGLPWFIKTAFTNASAPIEVNSKGLTYITISLNISILFLFLA 456

  Fly   568 VTTMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVEWDVV 608
            |....|.:.      |..||...::||.....:|..|..::
Mouse   457 VHFNGWKLD------RKLGVVCLVLYLGLATLSVLYEIGII 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	PLN03151	55..601	CDD:215604	125/552 (23%)
		Na_Ca_ex	450..601	CDD:426387	38/157 (24%)
Slc24a5	NP_778199.2	2A1904	<20..>229	CDD:273344	51/168 (30%)
		2A1904	<291..501	CDD:273344	57/296 (19%)