Protein Alignment CG14744 and Slc24a5

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_778199.2
• Gene: Slc24a5 / 317750
• MGIID: 2677271
• Length: 501
• Species: Mus musculus
• Alignment Length: 561
• Identity: 127/561 - (22%)
• Similarity: 209/561 - (37%)
• Gaps: 166/561 - (29%)

  Fly    75 VLFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV 139
            |::.|:..::|:|    :|.....||.|.|:|||..|.:::.:||.||:|.|:.:||::...:.|
Mouse    70 VIYFLIILYMCMA----ISIVCDKYFLPSLEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGV 130

  Fly   140 ---RADAPIFTITVGNTLAIILLSGGTVCFLRPFRMNGHSTL------RDLLFLLLGVEVLRFVM 195
               :.|..|.|| :|:  ||..|.|  :|.......|..|||      ||.....:.|..: |.:
Mouse   131 FITKGDIGISTI-LGS--AIYNLLG--ICAACGLLSNMVSTLSCWPLFRDCAVYAVSVGAV-FGI 189

  Fly   196 IKEGAVTLGEGIVLFLIYVVYVAINIADLALLRYYIRK-------LRRELDYLEGLTPPPITEIN 253
            |.:..:...||..|.|||.:||.:...|..:.|:.::.       |.|.:            |..
Mouse   190 IFDNRIYWYEGAGLLLIYGLYVLLLCFDTTISRHVMKTCSPCCPCLARAM------------EER 242

  Fly   254 AKIRKLISWEEQDDIGIKDTTKYRRSRDTGNHFSNMTSSGYFVTPIPERRSEHVDYELNRTALHD 318
            .:.:.|:.||::..:.|:     |:||         |.||.|        .|...|.....:||.
Mouse   243 IEQQTLLGWEDESQLFIR-----RQSR---------TDSGIF--------QEDSGYSQLSLSLHG 285

  Fly   319 ----SENPKNLQLFTEFFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHG 379
                ||:|                                    |.||.:    |..|..:|  .
Mouse   286 LSQVSEDP------------------------------------PSVFSM----PEADLRRI--F 308

  Fly   380 WSKLLNCTQIVTNPFVVITLVHSGVSSVYKTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDVPP 444
            |        :::.|  :|||:                        .||.|           |...
Mouse   309 W--------VLSLP--IITLL------------------------ALTTP-----------DCRR 328

  Fly   445 SYHHLFIILTFFSSMVTLWL-AVTELEV-LSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQL 507
            .:...:.::|||  |..||: |.|.:.| :..:.|....:.::.|.:|..|...:.||.:.:..:
Mouse   329 KFWKNYFVITFF--MSALWISAFTYILVWMVTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLV 391

  Fly   508 ALQGYGRMAFAAIIGGPVFAILV-----SMSLAFIFNHRVREVGANSWVYGDLGDNCYLFLVITI 567
            |.:|.|.||.:.|:|..||.:|.     .:..||.......||.:....|..:..|..:..:...
Mouse   392 ARKGKGDMAISNIVGSNVFDMLCLGLPWFIKTAFTNASAPIEVNSKGLTYITISLNISILFLFLA 456

  Fly   568 VTTMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVEWDVV 608
            |....|.:.      |..||...::||.....:|..|..::
Mouse   457 VHFNGWKLD------RKLGVVCLVLYLGLATLSVLYEIGII 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	48/150 (32%)
		Na_Ca_ex	450..601	CDD:279963	38/157 (24%)
Slc24a5	NP_778199.2	Na_Ca_ex	72..216	CDD:279963	48/153 (31%)
		TIGR00367	77..477	CDD:273039	121/538 (22%)
		Na_Ca_ex	334..485	CDD:279963	38/158 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810