Protein Alignment CG14744 and Slc24a5

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: XP_038960915.1
• Gene: Slc24a5 / 311387
• RGDID: 1310565
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 127/559 - (22%)
• Similarity: 202/559 - (36%)
• Gaps: 162/559 - (28%)

  Fly    75 VLFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV 139
            |::.|:..::.:|    :|.....||.|.|:|||..|.:::.:||.||:|.|:.:||::...:.|
  Rat    72 VIYFLITLYMFMA----VSIVCDKYFLPSLEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGV 132

  Fly   140 ---RADAPIFTITVGNTLAIILLSGGTVCFLRPFRMNGHSTL------RDLLFLLLGVEVLRFVM 195
               :.|..|.|| :|:  ||..|.|  :|.......|..|||      ||.....:.|..: |.:
  Rat   133 FITKGDIGISTI-LGS--AIYNLLG--ICAACGLLSNMVSTLSCWPLFRDCAVYAVSVGAV-FGI 191

  Fly   196 IKEGAVTLGEGIVLFLIYVVYVAINIADLALLRYYIRKLRRELDYLEGLTPPPITEINAKI---- 256
            |.:..|...||.:|.|||.:||.:...|..:.||..:..|            |.....||.
  Rat   192 IFDNRVYWYEGALLLLIYGLYVLLLCFDTTISRYVTKTCR------------PCCPCLAKAMEER 244

  Fly   257 ---RKLISWEEQDDIGIKDTTKYRRSRDTGNHFSNMTSSGYFVTPIPERRSEHVDYELNRTALHD 318
               :.|:.||.:..|.|:     |:||         |.||.|        .|...|.....:||.
  Rat   245 SEQQTLLGWENESQIYIR-----RQSR---------TDSGIF--------QEDSGYSQLSLSLHG 287

  Fly   319 ----SENPKNLQLFTEFFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHG 379
                ||:|.::       .|:...|.         .||:.:...|::.:|.|..|
  Rat   288 LSQVSEDPPSV-------FSMPEADL---------RRIFWVLSLPVITLLALTTP---------- 326

  Fly   380 WSKLLNCTQIVTNPFVVITLVHSGVSSVYKTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDVPP 444
                 :|.:.:...:.|||.                 |..:.|....|
  Rat   327 -----DCRRKLWKNYFVITF-----------------FMSAFWISAFT----------------- 352

  Fly   445 SYHHLFIILTFFSSMVTLWLAVTELEVLSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLAL 509
                          .|.:|:..        |.|....:.::.|.:|..|...:.||.:|:..:|.
  Rat   353 --------------YVLVWMVT--------ITGETLGIPDTVMGLTLLAAGTSIPDTVASVLVAR 395

  Fly   510 QGYGRMAFAAIIGGPVFAILV-----SMSLAFIFNHRVREVGANSWVYGDLGDNCYLFLVITIVT 569
            :|.|.||.:.|:|..||.:|.     .:..||.......||.:....|..:..|..:||:...|.
  Rat   396 KGKGDMAISNIVGSNVFDMLCLGLPWFIKTAFTNASAPIEVNSKGLTYITISLNISIFLLFLAVH 460

  Fly   570 TMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVEWDVV 608
            ...|.:.      |..||...:.||.....:|..|..::
  Rat   461 FNGWKLD------RKLGVVCLVSYLGLATLSVLYELGII 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	48/150 (32%)
		Na_Ca_ex	450..601	CDD:279963	35/155 (23%)
Slc24a5	XP_038960915.1	2A1904	<20..>241	CDD:273344	56/190 (29%)
		2A1904	<293..493	CDD:273344	54/292 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810