Protein Alignment CG14744 and Slc24a1

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_659062.1
• Gene: Slc24a1 / 214111
• MGIID: 2384871
• Length: 1130
• Species: Mus musculus
• Alignment Length: 806
• Identity: 131/806 - (16%)
• Similarity: 212/806 - (26%)
• Gaps: 388/806 - (48%)

  Fly    76 LFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV- 139
            :|.:::.|:.:|.:      ...||.|.|.:|:.||.::|.:||.||:|.|..:||:..:|:.|
Mouse   426 IFGMMYVFVALAIV------CDEYFVPALGVITHKLQISEDVAGATFMAAGGSAPELFTSLIGVF 484

  Fly   140 --RADAPIFTITVGNTLAIILLSGGTVCFLRP-FRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAV 201
              .::..|.||.......|:.:.|....|.|. ..:......||:.|.:|.:.:| .|...:..:
Mouse   485 ISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLFRDVSFYILDLSML-IVFFLDSFI 548

  Fly   202 TLGEGIVLFLIYVVYV------------------------AINIADL------------------ 224
            ...|.::|.|.|.:||                        .:.:.||
Mouse   549 AWWESLLLLLAYALYVFTMKWNKQIELWVKEQLSRRPVAKVMALGDLSKPSEDAVEENEQQDSKK 613

  Fly   225 ------------------ALLRYYIRKL-----------RRELDYLEGL---------------- 244
                              :::|..|..|           |...|..|.|
Mouse   614 LKLPSVLTRGSSSASLHNSIIRNTIYHLMLHSLDPLGEARPSKDKQESLNQEARVLSQTKAESSP 678

  Fly   245 -------------TPPPI----------------------------------TEINAK------- 255
                         ||.|.                                  ||...|
Mouse   679 DEDEPAELPAVTVTPAPAPDAKGDQEDDPGCQEDVDEAERRGEMTGEEGEKETETEGKKDEQEGE 743

  Fly   256 ---IRKLISWEEQ---------------------------------------------------- 265
               .||....||:
Mouse   744 TEAERKEDEQEEETEAEGKEQEGETEAEGKEDEQEGETEAEGKKDEQEGETEAEGKEEQEGETEA 808

  Fly   266 ----------------------------------------------------DDIGIKD------ 272
                                                                ||..:||
Mouse   809 EGKEDEQEGETEAEGKEEQEGETEAESKEVEQERETEAEGKDKHEGQGETQPDDTEVKDGEGETE 873

  Fly   273 --------TTKYRRSRDTGNHFSNMTSSGYFVTPIPERRSEHVDYELNRTALHDSENPKNLQLFT 329
                    .|:..:..|.|.......|         |...:..|.|.......:.|..:|.:
Mouse   874 ANAEDQCEATQGEKGADGGGESDGGDS---------EEEEDEEDEEEEEEEDEEEEEEENEE--- 926

  Fly   330 EFFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHGWSKLLNCTQIVTNPF 394
                   |:..| |........|||.. .|:||.|.|.||.|..::               :..|
Mouse   927 -------PLSLE-WPDSRQKQAIYLFL-LPIVFPLWLTIPDVRRQE---------------SRKF 967

  Fly   395 VVITLVHSGVSSVYKTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDVPPSYHHLFIILTFFSSM 459
            .|||.:.|                                               .|.:..||.:
Mouse   968 FVITFLGS-----------------------------------------------IIWIAMFSYL 985

  Fly   460 VTLWLAVTELEVLSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGP 524
            :..|         :..||....:||..|.:|..|...:.||:|.:..:|.:|.|.||.::.:|..
Mouse   986 MVWW---------AHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSN 1041

  Fly   525 VFAILVSMS---LAFIFNHRVREVGANSWVYGDLGDNC--------YLFLVITIVTTMWWSVTFD 578
            :|.|.|.:.   |.|...:.::.|..:|     .|..|        .||::.:|.:..|
Mouse  1042 IFDITVGLPVPWLLFSLINALQPVPVSS-----NGLFCAIVLLFLMLLFVIFSIASCKW------ 1095

  Fly   579 FHARRSAGVFLWLVYLQFLLYAVCVE 604
             ...:..|..::|:|..||:.:|.:|
Mouse  1096 -RMNKILGFTMFLLYFVFLVISVMLE 1120

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	39/169 (23%)
		Na_Ca_ex	450..601	CDD:279963	38/161 (24%)
Slc24a1	NP_659062.1	2A1904	1..1130	CDD:273344	131/806 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810