Protein Alignment CG14744 and ncx-5

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_505690.2
• Gene: ncx-5 / 191715
• WormBaseID: WBGene00003570
• Length: 656
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 122/620 - (19%)
• Similarity: 221/620 - (35%)
• Gaps: 173/620 - (27%)

  Fly    78 MLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV--- 139
            :|::.|:.:|.:      ...:|.|.|.:|:..|.:::.:||.||:|.|..:||...:|..|
 Worm   105 LLIYMFVALAVV------CDEFFVPSLSVITEVLAISDDVAGATFMAAGGSAPEFFTSLFGVFVA 163

  Fly   140 RADAPIFTITVGNTLAIILLSGGTVCFLRP-FRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAVTL 203
            :.:..:.||....|..|:.:......|.|. ..:......||:.|..|.:.:| .:...:..:..
 Worm   164 QDNVGVGTIVGSATFNILCVLAFCTLFSRQVLHLTWWPLFRDMSFYTLSLFLL-LIFFGDEVIEW 227

  Fly   204 GEGIVLFLIYVVY---VAIN-IADLALLRYYIRKL--------RRELDYLEGLTP---------- 246
            .|.:|:|.:|:.|   :..| ..:|...::..||:        ...:|...|.||
 Worm   228 QEALVMFSMYIAYGFFMKFNGFLELKTKQFLFRKVGIGSEIAPETIVDAAAGCTPRSPHSLGAQG 292

  Fly   247 -----PPI---TEINAKIRKLISWEEQDDIGIKDTTKYRRS------------------------ 279
                 |.|   .|:...|.:|:..:|.|......::...||
 Worm   293 PRRSFPMIHGGQEVRKSIAQLVIGDEDDTSSSSSSSSSERSNKIKPVSNGVPEIRQNGRTIMVKP 357

  Fly   280 -RDTGNHFSNMTSSGYFVTPIPERRSEHVDYELNRT-ALHDSENPK----NLQLFTEFFQSLNPV 338
             .|....|:|..|....:|||        |:..:.| .::::.|.|    |...:....:::||.
 Worm   358 ANDPDAKFNNQNSIKTVITPI--------DFGDDHTIVINNNNNGKRKNGNNGTYLTPVEAINPS 414

  Fly   339 DAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHGWSKLLNCTQIVTNPFVVITLVHSG 403
            :..                                          |...|...||...|.|.:..
 Worm   415 NGH------------------------------------------LELAQTNGNPVPPIALDNLS 437

  Fly   404 VSSVYKTWHITLDFS---------ISMWSPCLTVPLAIVIFLHSRTDV-PPSYHHLFIILTFFSS 458
            ::|  .|....||.|         |.::...:|.|||     ::..|| .||....|.| ||..:
 Worm   438 IAS--STAEKPLDLSWPEANHKKLIYLFLAPITFPLA-----YTLPDVRKPSLRKFFAI-TFIGA 494

  Fly   459 MVTLWLAVTELEVL--SEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAII 521
            :  ||:|.....::  :..:|..|.:....|.:|..|...:.||:|.:..:|.:|.|.||.::.|
 Worm   495 I--LWIAAYSYLMVWWANTIGETFGIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSI 557

  Fly   522 GGPVFAILVSMSLAFIFNHRVR----------EVGANSWVYGDLGDNC-------YLFLVITIVT 569
            |..:|.:.|.:.:.::.:..:.          .|.:|..|       |       .|.:::|.|.
 Worm   558 GSNLFDVCVGLPIPWLIHFAIGVFKSEPTQNISVTSNGLV-------CSLGLLFAMLIVLLTCVA 615

  Fly   570 TMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVE 604
            ...|.:...|      |:.:...|..|.:..:.:|
 Worm   616 ISRWKMDKFF------GLLMIFSYCGFCMLCILLE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	35/149 (23%)
		Na_Ca_ex	450..601	CDD:279963	36/169 (21%)
ncx-5	NP_505690.2	Na_Ca_ex	102..244	CDD:279963	34/145 (23%)
		Na_Ca_ex	486..642	CDD:279963	36/171 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810