Protein Alignment CG14744 and ncx-10

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_001256094.1
• Gene: ncx-10 / 190821
• WormBaseID: WBGene00003575
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 129/619 - (20%)
• Similarity: 247/619 - (39%)
• Gaps: 139/619 - (22%)

  Fly    76 LFMLLFAFICVAFLW-LMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV 139
            :.:::.:.|.:.||: :|:.....:|||.:..|...|.::|.:||||||||||.:|::..::..|
 Worm   101 IILIIISIIYLLFLFVVMTVVADDFFSPSIAGIVRHLKISESIAGVTFLAFGNGAPDVFGSIASV 165

  Fly   140 ------RADAPIFTITVGNTLAIILLSGGTVCFLRPFRMNGHSTLRDLLFLLLGVEVLRFVMIKE 198
                  :||..|..| :|..:.:..:....:...:.||:...:|:||::|.::....|....:..
 Worm   166 ITTPKPKADLAIGDI-IGGGIFVTTVVLSAIILTKSFRIAILATIRDIVFFIIADIFLAIWFLTF 229

  Fly   199 GAVTLGEGIVLFLIYVVYVAINIADLALLRYYIRKLRRE-------------------------- 237
            ..|.:...:....:|..||    ..:.|:|...::.:|.
 Worm   230 NHVEIWMPLTFLGLYAAYV----VSVILMRLNSKRRKRARHEKIENARKESAMNHHTHKISTFIG 290

  Fly   238 --LDY---LEGLTPPPITEINAKIRKLISWEEQD-DIGIKDTTKYRRSRDTGNHFSNMTSSGYFV 296
              :||   :.......|:.:...::..:..:|.. :.|:.|.|......:...|:::
 Worm   291 FFMDYAHVINFFANNKISSMTNNVKNFLDGKEDSLEDGLVDETSDDEGVEAEFHYAH-------- 347

  Fly   297 TPIPERRSEHVDYELNRTALHDSE--NPKNLQLFTEFFQSLN------PVDAEAWQLGGWSNRIY 353
                  |..:..|:....|..|.|  .||..:.: |:.:.:.      |.:.|.:::..:|..|.
 Worm   348 ------RHVYKSYDEASLAFTDVEEIQPKTWKSW-EWVRDVRNHLRPWPGNDEFYEMNYFSRFIT 405

  Fly   354 LIARCPLVFVLQLFIPVVDYEKIKHGWSK---LLNCTQIVTNPFVVITLVHSGVS-SVYKTWHIT 414
            ::|..| .|.|:|.||..:..     |||   :::|       |..|.|....|. |....:|
 Worm   406 VVAVIP-TFFLKLTIPSNEMP-----WSKPILIIHC-------FCSIQLALFAVQISAKSPFH-- 455

  Fly   415 LDFSISMWSPCLTVPLAIVIFLHSRTDVP-----PSYHHLFIILTFFSSMVTLWLAVTELEVLSE 474
              .|..:|...|.:  :|::.|.:....|     ..|..::..|.|..|:.  |:.....|:::.
 Worm   456 --GSPGLWLYGLLI--SIILSLLALRFTPLDREQKYYREVYSYLGFLMSIA--WIYTISSEIINV 514

  Fly   475 I--VGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGPVFA---------- 527
            |  :|:...:|:..:.:|..|.||...||:::..:..||:.:||.||.||||:|:
 Worm   515 ITMIGVATGVSQEILGLTIMAWSNCIGDIVSDVAVVKQGFPKMAMAAAIGGPLFSKLYSRPCQIK 579

  Fly   528 -------ILVSMSLAFIFNHRVREVGANSWVYGDLGD--------NCYLFLVITIVTTMWWSVTF 577
                   :|:...|.|..          :.:.|...|        ...|||.|::.|::......
 Worm   580 ITTYISDLLIGFGLPFTI----------ACLQGKQIDLIITPVYRLLMLFLAISLFTSLIAIFVQ 634

  Fly   578 DFHARRSAGVFLWLVYLQFLLYAV-----CVEWD 606
            .|..|....|.|..|::.||::.:     .:||:
 Worm   635 RFKVRWPHAVALLTVFVAFLIFVLLSETHTLEWN 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	38/148 (26%)
		Na_Ca_ex	450..601	CDD:279963	42/177 (24%)
ncx-10	NP_001256094.1	PLN03151	35..571	CDD:215604	110/510 (22%)
		Na_Ca_ex	113..253	CDD:279963	37/144 (26%)
		Na_Ca_ex	492..659	CDD:279963	42/178 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I5893
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41602
Inparanoid	1	1.050	162	1.000	Inparanoid score	I2840
Isobase	1	0.950	-	0	Normalized mean entropy	S4675
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm4752
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.930