Protein Alignment CG14744 and ncx-9

DIOPT Version :10

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: NP_504342.2
• Gene: ncx-9 / 182576
• WormBaseID: WBGene00003574
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 160/667 - (23%)
• Similarity: 269/667 - (40%)
• Gaps: 164/667 - (24%)

  Fly    55 FFNYFRMMYCSIDIDDKATEVLFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAG 119
            :..:...:.|..:|..:.  :|.:|...::.:.|: :||.....:|.|.:..|...|.|:|.:||
 Worm    84 YLTWSHYVKCQYNIGVRV--ILIILGILYLIILFV-IMSSIADDFFCPAISGIVSHLRMSESIAG 145

  Fly   120 VTFLAFGNCSPEIIANLMPV------RAD--------APIFTITVGNTLAIILLSGGTVCFLRPF 170
            ||||||||.:|::.:::..|      :||        ..||..||  .||||:       |.:.|
 Worm   146 VTFLAFGNGAPDVFSSISSVLTTPKPKADLALGDLFGTSIFVTTV--VLAIII-------FTKSF 201

  Fly   171 RMNGHSTLRDLLFLLLGVEVLRFVMIKEGAVTLGEGIVLFLIYVVYVAINIADLALLRYY----- 230
            ::....|||||:|.:..:..:.|..:|...:.:........||.||| :.:..|.:.|.:
 Worm   202 KVAIIPTLRDLIFYMTTLAFIVFCFLKFDKIEVWMPATFLGIYGVYV-VTVIILGIYRTHRKKRN 265

  Fly   231 IRKLRREL-DYL----EGLTPPPI----------TEINAKIRKLISWEEQDDIGIKDTTKYRRSR 280
            ::|..:|| |:|    ...:..||          ..::|....:|.:.:    .||:.|:....|
 Worm   266 LKKKNKELEDFLSRPSSAASTTPIFGAMKLKEETISVSALFHFMIGYSQ----FIKNLTRANLKR 326

  Fly   281 DTGNHFSN-------MTSSGYFVTP--IPERRSEHVDYELN--RTALHDSENPKNLQ-------- 326
            .|.|:.::       :.:.| |..|  ||..|.....::.|  .|.|...|:..:|.
 Worm   327 TTNNNNNDNKNEKRGIVNLG-FSEPYSIPSERKISTIFKQNTFETDLESLESLADLDGSDDEGRE 390

  Fly   327 ---------LFTEFFQ------SLNPVDAEAWQ-----------LGGWSNR-----------IYL 354
                     :||...|      .:..::...|:           |..|.:|           |..
 Worm   391 EKFGYAHHTVFTSHDQISLVASEIEEIEITTWRSWDWVWDLFNHLKSWPSRDEFSEMNIFIKIVT 455

  Fly   355 IARCPLVFVLQLFIPVVDYEKIKHGWSK---LLNC----------TQIVT-NPFVVITLVHSGVS 405
            :.:...||..:|.:|     ..:..|.|   :|:|          .||:| .||       .|..
 Worm   456 VIKVVPVFFFKLTVP-----SNEMSWCKPLFILHCFASIQFALFSIQIITLKPF-------DGSP 508

  Fly   406 SVYKTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDVPPSYHHLFIILTFFSSMVTLWLAVTELE 470
            .:   |...|.||        .:...:.::....:.....|..::..|.|..|:.  |:..|..|
 Worm   509 GL---WLYGLGFS--------AILAMVAMYFLPLSKEQKYYKEIYSYLGFLMSIA--WIYATSNE 560

  Fly   471 VLSEI--VGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGPVFAILVSMS 533
            ::|.:  :|:|..||...:.:|..|.||...||:|:..:..|||.:||.||.||||:|.:|:...
 Worm   561 IVSVVTMIGVVTGLSMELLGLTIMAWSNCIGDIVADIAVVKQGYPKMAMAAAIGGPLFNLLIGFG 625

  Fly   534 LAFIF---NHRVREVGANSWVYGDLGDNCYLFLVITIVTTMWWSVTFDFHARRSAGVFLWLVYLQ 595
            |.|..   ..:..|:..|. ||..|    .|||.|::|||........|..||...|.|..:::.
 Worm   626 LPFTIAAAQGKEMELLINP-VYRLL----MLFLGISLVTTFVALFIQRFTVRRPHAVLLIFIFVV 685

  Fly   596 FLLYAVC------VEWD 606
            ||:: :|      :||:
 Worm   686 FLIF-ICLAEFHVLEWN 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	PLN03151	55..601	CDD:215604	157/654 (24%)
		Na_Ca_ex	450..601	CDD:426387	52/155 (34%)
ncx-9	NP_504342.2	PLN03151	68..689	CDD:215604	157/652 (24%)