Protein Alignment CG14744 and slc24a1

DIOPT Version :10

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: XP_017947991.2
• Gene: slc24a1 / 100488363
• XenbaseID: XB-GENE-991430
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 647
• Identity: 122/647 - (18%)
• Similarity: 225/647 - (34%)
• Gaps: 204/647 - (31%)

  Fly    76 LFMLLFAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV- 139
            :|.:::.|:.:|.:      ...:|.|.|.:|:.||.::|.:||.||:|.|..:||:..:|:.|
 Frog   159 IFGMMYVFVALAIV------CDEFFVPALGVITEKLQISEDVAGATFMAAGGSAPELFTSLIGVF 217

  Fly   140 --RADAPIFTITVGNTLAIILLSGGTVCFLRP-FRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAV 201
              .::..|.||.......|:.:.|....|.|. ..:......||:.|.:|.: ::..:...:..:
 Frog   218 ISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWPLFRDVSFYILDL-IMLIIFFLDNVI 281

  Fly   202 TLGEGIVLFLIYVVYVA---INIADLALLRYYIRKLRR--ELDYLEGLT-----------PPPIT 250
            ...|.::|.|.|.:||.   :|:....|::..:.|.||  ::..||..:           |.|:.
 Frog   282 QWWESMLLLLAYGLYVGFMKLNVQVERLVKGQLSKQRRLVKVMALEDTSKKGNGAVAQDEPKPVE 346

  Fly   251 EIN-AKIRKLISWEEQDDIGIKDTTKYRRSRDTGNHFSNMTSSGY-----FVTPIPERRSEHVDY 309
            :.| .:::..::               |.......|.|.|.|:.:     .:.|:.|..:
 Frog   347 DNNRLRLKPFLT---------------RGGSSASLHNSTMRSTIFQLMIHTLDPLGEASN----- 391

  Fly   310 ELNRTALHDSENPKNLQLFTEFFQSLNPVDAEAWQLGGWSNRIYLIAR-------CPLVFVLQLF 367
             ||:......||....:...|...:|.....|.....|      |.|:       .|....:::.
 Frog   392 -LNQCRPCYPENGAKFKDKAEIMNNLAKAKVETEAKKG------LKAKDDKDETDVPNTVNVEVT 449

  Fly   368 IP------------VVDYEKIKHG----------------------------------------- 379
            .|            |:|.:.||.|
 Frog   450 PPTGSEPSGDAEDEVMDKDDIKRGRGEGGGGGDSSGSSGDESDDDSDDEDSDDDDDDDDDDDDDD 514

  Fly   380 ----------------W--SKLLNCTQIVTNPFVVITLVHSGVSSVYKTWHITLDFSISMWSPCL 426
                            |  :|....|.:...|.|                       ..:|   |
 Frog   515 GEGEEEEEADEPLSLEWPETKRKQITYLFLLPIV-----------------------FPLW---L 553

  Fly   427 TVPLAIVIFLHSRTDVPPSYHHLFIILTFFSSMVTLWLAVTELEVL--SEIVGIVFNLSESFMAV 489
            |:|           ||.......:.:|||..|:  :|:||....::  :..||....:||..|.:
 Frog   554 TLP-----------DVRTPKSRNYFVLTFLGSI--MWIAVFSYLMVWWAHQVGETIGISEEIMGL 605

  Fly   490 TFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGPVFAILVSMSLAF----IFNHRVREVGANSW 550
            |..|...:.||:|.:..:|.:|.|.||.::.:|..:|.|.|.:.:.:    :||      |.:..
 Frog   606 TILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWFLFSVFN------GFSPV 664

  Fly   551 VYGDLGDNC--------YLFLVITIVTTMWWSVTFDFHARRSAGVFLWLVYLQFLLYAVCVE 604
            .....|..|        .||::.:|....|       ...:..|..::::|..|::.:|.:|
 Frog   665 PVSSNGLFCAIVLLFLMLLFVIFSIAACKW-------KMNKFLGFTMFILYFVFVIVSVMLE 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	PLN03151	55..601	CDD:215604	120/642 (19%)
		Na_Ca_ex	450..601	CDD:426387	38/164 (23%)
slc24a1	XP_017947991.2	2A1904	<92..729	CDD:273344	122/647 (19%)