Protein Alignment CG14744 and slc24a4b

DIOPT Version :9

• Sequence 1: NP_001097232.2
• Gene: CG14744 / 35858
• FlyBaseID: FBgn0033324
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: XP_002665845.2
• Gene: slc24a4b / 100334346
• ZFINID: ZDB-GENE-081031-75
• Length: 636
• Species: Danio rerio
• Alignment Length: 604
• Identity: 129/604 - (21%)
• Similarity: 212/604 - (35%)
• Gaps: 212/604 - (35%)

  Fly    76 LFMLL-FAFICVAFLWLMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPV 139
            |:|.| .|.:|           ..||...|:.|..||:::|.:||.||:|.|:.:||:.|:::.|
Zfish   161 LYMFLALAIVC-----------DDYFVTSLEKICEKLNLSEDVAGATFMAAGSSAPELFASVIGV 214

  Fly   140 ---RADAPIFTI---TVGNTLAIILLSG---GTVCFLRPFRMNGHSTLRDLLFLLLGVEVLRFVM 195
               ..|..:.||   .|.|.|.||.:.|   |.|..|     ...:..||..|.:|.|..| .|.
Zfish   215 FITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVLL-----TWWAVFRDSFFYILSVVAL-IVF 273

  Fly   196 IKEGAVTLGEGIVLFLIYVVYVAINIADLALLRYYIRKLRRE----------------------- 237
            |.:..:...|.:||.::|..|:.|...:..|.:::.||..:.
Zfish   274 IYDEKIVWWESLVLVVMYACYILIMKFNSRLQKFFTRKGNKNVANGNAAAGSELEDVKTSKIYSR 338

  Fly   238 -----LDYLEGLTPPPITEINAKIRKLISWEEQDDIGIKDTTKYRRSRDTGNHFSNMT----SSG 293
                 :|.:...:||......|.:|.:::                      |||...|    :|.
Zfish   339 GSVVMVDEIINASPPNYRFPEAGLRVMVT----------------------NHFGPKTRLRMASR 381

  Fly   294 YFVTPIPERR--------------SEHVDYELNRTALHDSENPKNLQLFTEFFQSLNPVDAEAWQ 344
            ..:|   ||:              ....|.|........|...|..:|.|.|            :
Zfish   382 LIIT---ERQRLVQSANGVETAVVDGKPDIENGNVPEDKSTEEKESELTTPF------------R 431

  Fly   345 L-GGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHGWSKLLNCTQIVTNPFVVITLVHSGVSSVY 408
            | .|..||...:...||:.:|...||               ||.:
Zfish   432 LPDGCMNRTKWLISWPLLLILFFTIP---------------NCAK-------------------- 461

  Fly   409 KTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDVPPSYHHLFIILTFFSSMVTLWLAVTE--LEV 471
                       |.|..                         :.:|:|..|  |:|:||..  :..
Zfish   462 -----------SRWEK-------------------------YFMLSFILS--TVWIAVFSYFMVW 488

  Fly   472 LSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGPVFAILVSMSLAF 536
            :..|:|....:.:..|.:||.|...:.||.||:..:|.||.|.||.:..||..||.|||.:.:.:
Zfish   489 MVTIIGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPW 553

  Fly   537 IFNHRVREVGANSWVYGD---LGDNCYLFLVITIVTTM----------WWSVTFDFHARRSAGVF 588
                .::.:..|   ||.   :.....|:.|:.::.::          .|.:.|      ..||:
Zfish   554 ----ALQTMAVN---YGSVVMINSRGLLYSVVLLLGSVALTILGIHLNHWKLDF------KLGVY 605

  Fly   589 LWLVYLQFLLYAVCVEWDV 607
            :.|:|..||.:::.:|::|
Zfish   606 VLLLYAVFLCFSIMIEYNV 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	46/151 (30%)
		Na_Ca_ex	450..601	CDD:279963	43/165 (26%)
slc24a4b	XP_002665845.2	TIGR00367	155..581	CDD:273039	119/553 (22%)
		Na_Ca_ex	156..298	CDD:279963	47/153 (31%)
		Na_Ca_ex	467..619	CDD:279963	43/166 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840