DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12376 and CAX11

DIOPT Version :9

Sequence 1:	NP_610405.3	Gene:	CG12376 / 35857	FlyBaseID:	FBgn0033323	Length:	617	Species:	Drosophila melanogaster
Sequence 2:	NP_172370.3	Gene:	CAX11 / 837416	AraportID:	AT1G08960	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	139/577 - (24%)
Similarity:	227/577 - (39%)	Gaps:	141/577 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 VLPYMRIMACDLNCVNEFEQVIFLALFMGLCYEILVLLIHVCNKYYSPALKAVSRFLCMNEHVAG 116
            |:.|..:..|..| .|.|..:..|:|.:.|.:.|   ||.....::|.....::..|.::..:|.
plant    74 VINYFSLHYCIFN-ENLFFSIPILSLLILLHFYI---LIKTAQTHFSTVTTKLADRLNLSPSMAA 134

  Fly   117 VTLLAFGNSSADLFSNLASVNANV--PVFANSLAAALFVS-MVSGGLICYTSPFKMNAYESVRDI 178
            |||||.||.:.|:|:::|::....  ..|...|:|..||| .|.|.:..|.:||.::|...|||:
plant   135 VTLLALGNGAPDVFASVAALRGGQYRTGFGAILSAGTFVSAFVVGFVAIYAAPFPVDAASFVRDV 199

  Fly   179 LFLIFGSMLLQY-FLASSAHVPE----TSFIVMFLVYIFYILVNVVDVYLIRRALKTTNAQIDAL 238
            ||.:..::.|.| :|:....|.:    ..|.:.|:.::|::...             ||.
plant   200 LFYLIAALFLFYVYLSGEIFVWQAIGFVGFYIFFVGFVFWMDFG-------------TNV----- 246

  Fly   239 LVGEMTPEKRKRLSELERNQAIYTRDMEVEI-------FERTNSGPNINKIRYTTLRMGRSTRIS 296
                   ||.|.:|| |....:..:|.|:..       .|:.:....|.::..|..||. .|.:|
plant   247 -------EKGKSISE-EEKDLLRLQDCEIAAGSLGSYKAEKEHQFSGIFRLYGTISRMW-ETPVS 302

  Fly   297 LDRKATRMVLHNRALGR----NWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIY 357
                    ||.|..:.:    .|..|              :|..||:...|.|
plant   303 --------VLLNLTIPKPSPSEWSRF--------------YRSANIVFCPFAL------------ 333

  Fly   358 IPLVDYELDKHGWNKLLNCIQ-VMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPI-- 419
                           |..|.. |.||..:|.     |..:....||.|.:...:..|.....:
plant   334 ---------------LYTCNSFVQLNHPISF-----LFPNTHLPLWLVVLFMTSSLAFLHFTVEK 378

  Fly   420 ------TVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDD 478
                  .:|:.|..||.          |||.:..:.|          |:...|..:|.:||:...
plant   379 QPPKTEQLPVIVVAFIM----------SVFWISTIAG----------ELLNCLAALGTLLKLPPA 423

  Fly   479 FMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVV--MSASTVMHVKNLFGLPVSE 541
            .:|.||.|...|:|.|:|:||:|..|.|.||.|....||.|.::  :.::.||...|::    .:
plant   424 LLGLTVLAWGNSVGDLVADVAVAKAGRPAMAMAGCFAGPMFNMLVGLGSALVMQTANVY----PD 484

  Fly   542 ANQTG-NYGL-NAFIFLNLGVFSTLLWSTTLGFFARRSVGIFSIVFYCIYLLFAILI 596
            |.:.| :.|: .||:||.|.:..:||..|...|...|..||..:..|..:...:::|
plant   485 AYKLGFHVGIVIAFVFLLLSLMGSLLVITWSRFRVPRFWGICLVGLYVAFTFVSLII 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	138/571 (24%)
		Na_Ca_ex	85..219	CDD:279963	40/141 (28%)
		Na_Ca_ex	448..595	CDD:279963	44/150 (29%)
CAX11	NP_172370.3	PLN03151	72..539	CDD:215604	138/573 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	LDO	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.790