Protein Alignment CG12376 and slc24a2

DIOPT Version :9

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_017211234.1
• Gene: slc24a2 / 751686
• ZFINID: ZDB-GENE-060825-277
• Length: 628
• Species: Danio rerio
• Alignment Length: 614
• Identity: 127/614 - (20%)
• Similarity: 240/614 - (39%)
• Gaps: 147/614 - (23%)

  Fly    40 VASAKDCNRSTNVLPYMRIMACDLNCVNEFEQVIFLALFMGLCYEILVLLIHVCNKYYSPALKAV 104
            :|.|.....|....|.      ||..:.:..|...:....|:.|..:.|.| ||::::.|||..:
Zfish   104 IAMASSAEHSKGEYPE------DLFTLEQRRQGAVVLHMFGMMYMFIALAI-VCDEFFVPALTVI 161

  Fly   105 SRFLCMNEHVAGVTLLAFGNSSADLFSNLASV---NANVPVFANSLAAALFVSMVSGGLICYTSP 166
            :..|.:::.|||.|.:|.|.|:.:||:::..|   ::||.: ...:.:|:|..:...|:....|.
Zfish   162 TEKLEISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGI-GTIVGSAVFNILFVIGMCALFSR 225

  Fly   167 FKMNA--YESVRDILFLIFG-SMLLQYFLAS-SAHVPETSFIVMFLVYIFYILVN-VVDVYLIRR 226
            ..:|.  :...||:.|.|.| .||:.:||.: ..:|...:.:..:..|:.::..| .|:.::..|
Zfish   226 EILNLTWWPLFRDVSFYIIGLIMLIVFFLDNYITYVESFALLSCYGSYVTFMKFNSSVETWIKTR 290

  Fly   227 ALKTTNAQIDALLVGEMTPEKRKRLSELERNQAIYTRDMEVEIFERTNSGPNINKIRYTTLRMGR 291
            .|   ..|:|.:   |..|            :.:...|.|             ||:
Zfish   291 LL---GNQVDDI---EAPP------------KVVSVPDDE-------------NKL--------- 315

  Fly   292 STRISLDRKATRMVLHNRALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKI-------- 348
            |.:..|.|..:...||| .|.|| .:|:.:...|.|::     :|...::|.:|.||
Zfish   316 SAKPRLQRGGSSASLHN-TLMRN-SIFQLMIHTLDPLS-----EGKFKEKASILHKIARKKGQDE 373

  Fly   349 -----PAVIICCIYIPLVDYELDKHGWNKLLNCIQVMLNPAMSIMAIKALLSSRGNSL------- 401
                 .....|.:        :||:..|.  :.::|.:.|.|:        .|.|..:
Zfish   374 ANGVEDGQRKCML--------MDKNLPNS--SNVEVEVTPPMN--------GSAGPEVEVEEEEE 420

  Fly   402 ---------WYVAMGEEAIYAMYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSM----F 453
                     |...:.::..| ::..||..|:.:     |..||.......|..:...||:    |
Zfish   421 DEDQPLSLAWPDTIRKQVTY-LFIFPIVFPLWL-----SLPDVRRESSRKFFPVTFLGSISWIAF 479

  Fly   454 MIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPF 518
            ..::......:|.|.||    :.::.||.|:.|...|:..||.:|.:|..|...||.:|::|...
Zfish   480 FSYLMVWWAHQVGETIG----ITEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNI 540

  Fly   519 FTVVMSASTVMHVKNLFGLP-----VSEANQTGNYGLN------AFIFLNLGVFSTLLWSTTLGF 572
            |.:.:            |||     .|..|...:..::      |.:.|.|.:...::......:
Zfish   541 FDITV------------GLPFPWLLFSMLNDFSSVAVSSNGLFCAIVLLFLMLLFVIISIAVCKW 593

  Fly   573 FARRSVGIFSIVFYCIYLLFAILIHRKVI 601
            ...:.:|....:.|.::|:.::::..|:|
Zfish   594 KMSKMLGFLMFLLYFVFLVVSVMLEDKII 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	125/603 (21%)
		Na_Ca_ex	85..219	CDD:279963	37/141 (26%)
		Na_Ca_ex	448..595	CDD:279963	33/161 (20%)
slc24a2	XP_017211234.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810