Protein Alignment CG12376 and slc24a6a

DIOPT Version :10

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_021329984.2
• Gene: slc24a6a / 561209
• ZFINID: ZDB-GENE-100922-39
• Length: 639
• Species: Danio rerio
• Alignment Length: 627
• Identity: 133/627 - (21%)
• Similarity: 233/627 - (37%)
• Gaps: 171/627 - (27%)

  Fly    66 VNEFEQVIF-----------LALFMGLCYEILVLLIHVCNKYYSPALKAVSRFLCMNEHVAGVTL 119
            ::||.|.||           |.:|..: |....|.| ||:.::.|:|:.:...|.::|.|||.|.
Zfish    89 IHEFPQDIFTKGQRRHGAILLHVFCAV-YMFYALAI-VCDVFFVPSLEKICENLHLSEDVAGATF 151

  Fly   120 LAFGNSSADLFSNLASV---NANVPVFANSLAAALFVSMVSGGL--ICYTSPFKMNAYESVRDIL 179
            :|.|:|:.:||::|..|   ..::.| ...:.:|:|..:|..|:  |.......:..:...||.:
Zfish   152 MAAGSSAPELFTSLIGVFITKGDLGV-GTIVGSAVFNILVIIGVCGIFAGQTITLTWWPLFRDSI 215

  Fly   180 FLIFGSMLLQYFLASSAHVPETSFIVMFLVYIFY----------ILVNVVDVYLIRRALKTTNAQ 234
            |.|..                    |:.|:.|.|          ||:::..||::   :...|:|
Zfish   216 FYILS--------------------VLALILIIYDEKVIWWETIILISMYGVYIL---IMKFNSQ 257

  Fly   235 I---------------------DALLVGEMTPEKRKRLSELERNQAIYTRDMEVEIFERTNS-GP 277
            |                     ..:.|||.:|.....:..|::.|....:|..|.:.:...| .|
Zfish   258 IWGWVEQRFGIPGQPCLVSSLRRDVSVGEASPHCDTSMILLKKGQNAGGQDSPVVMVDELMSLHP 322

  Fly   278 NINKIRYTTLRM------GRSTRISLDRKATRM-------VLHNRALGRN--------------- 314
            :.......:||:      ...||:|:   |.||       ::.||:.|.:
Zfish   323 HQFSFSEASLRVMITPHFSPRTRLSM---AGRMLITERQRLIRNRSPGDSSGSGAGDTPGQDGPG 384

  Fly   315 -----WGLFKD--LFIALRPINCEKWR-KGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKHGWN 371
                 |||...  |....:|:...:.| :|..::|...:....         |..|.|.::....
Zfish   385 MEAVPWGLENGGALESETQPLEEPRRRSQGGELERVADIEDTQ---------PKDDEEDEEEADE 440

  Fly   372 KLLNCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPI------TVPIAVFMFIQ 430
            :......|                  ....|     |:|.: |:|.|:      |||..|.
Zfish   441 EPFRPFTV------------------PEGRW-----EQAKW-MFSWPLSCLLYYTVPNCVL---- 477

  Fly   431 SRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLI 495
                  |.:...|.| ....|...|.:.:..:..::.:|...|.:.|..||.|..|...|:...:
Zfish   478 ------PRWERWFMV-TFVASTLWIAVFSYLMVWMVTIISFTLDIPDVVMGITFLAAGTSVPDCM 535

  Fly   496 ANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNL---FGLPVSEANQTGNYGLNAFIFLN 557
            |::.:|..|...||.:::||...|.:::.......::.|   :|..|| .|..|.  :.:.|.|.
Zfish   536 ASLIVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLVVDYGSTVS-INSKGL--VYSVILLL 597

  Fly   558 LGVFSTLLWSTTLGFF-ARRSVGIFSIVFYCIYLLFAILIHR 598
            ..||.|:| |..|..: ..|.:|:..:..|.|:||.:|...:
Zfish   598 ASVFLTVL-SVHLNHWRLDRRLGLGLMFLYAIFLLCSICFEK 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	131/619 (21%)
slc24a6a	XP_021329984.2	None