Protein Alignment CG12376 and slc24a1

DIOPT Version :9

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_009291877.2
• Gene: slc24a1 / 558299
• ZFINID: ZDB-GENE-060503-191
• Length: 741
• Species: Danio rerio
• Alignment Length: 672
• Identity: 127/672 - (18%)
• Similarity: 238/672 - (35%)
• Gaps: 209/672 - (31%)

  Fly    54 PYMRIMACDLNCVNEFEQVIF-----------LALFMGLCYEILVLLIHVCNKYYSPALKAVSRF 107
            |:|:         .|:.:.||           |.:| |:.|..:.|.| ||::::.|.|..::..
Zfish   149 PHMK---------GEYPEDIFSIEDRRKGWVSLHIF-GMVYMFVSLAI-VCDEFFVPTLGVITDK 202

  Fly   108 LCMNEHVAGVTLLAFGNSSADLFSNLASV---NANVPVFANSLAAALFVSMVSGGLICYTS--PF 167
            |.:::.|||.|.:|.|.|:.:||::|..|   ::||.: ...:.:|:|..:...|:....|  ..
Zfish   203 LAISDDVAGATFMAAGGSAPELFTSLIGVFISHSNVGI-GTIVGSAVFNILFVIGMCALFSREML 266

  Fly   168 KMNAYESVRDILFLIFG-SMLLQYFLASSAHVPETSFIV-MFLVYIFYILVNVVDVYLIRRALKT 230
            .:..:...||:.|.|.. .||:.:||.::....|:..:| .:.:|:.::..||    .:.||.|:
Zfish   267 HLTWWPLFRDVSFYILDLIMLIIFFLDNTIMWWESMMLVGGYALYVTFMKFNV----QLERAFKS 327

  Fly   231 TNAQ----IDALLVGEMTPEKRKRLSELERNQAIYTRDMEVEIFERTNSGPNINKIRYTTLRMGR 291
            ..::    :..:.|.|  |||....|..|      .|..|.|...|....|        ||:.|.
Zfish   328 QLSKHKSIVKVIAVEE--PEKDNGTSGEE------NRPPEPEDKNRLKLKP--------TLQRGG 376

  Fly   292 STRISLDRKATRMVLHNRALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCI 356
            |:          ..|||..: || .:|:.:...|.|:..|....|:...|:.:..|:
Zfish   377 SS----------ASLHNSTM-RN-TIFQLMIHTLDPLGEESVFNGDAKARSSLECKV-------- 421

  Fly   357 YIPLVDYELDKHGWNKLLNCIQVMLNPAMSIMAIKAL---------------------------- 393
                           |..:..|::.:.|...:..|..
Zfish   422 ---------------KFKDKAQILNDMARGKVENKKKEKSGEGDDQSEQTKDSKDAPPGAKDEDT 471

  Fly   394 -----------LSSRGNS----------------------------------------------- 400
                       :::.|.|
Zfish   472 NQKSEAQKDGDIAAGGGSENPGGSDNSGDDDEDDSDEESDDDDDDDDDDDDDDDENEDEAGEDGD 536

  Fly   401 -----LWYVAMGEEAIYAMYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMFMIFICAT 460
                 .|.....::|.| ::.|||..|:.:.:     .||.......|.|:...||:..|.|.:.
Zfish   537 EPLSLEWPDTRRKQATY-LFLLPIVFPLWLTV-----PDVRNPASKKFFVITFLGSIVWIAIFSY 595

  Fly   461 EIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSA 525
            .:......:|..:.:.::.||.|:.|...|:..||.:|.:|..|...||.:|::|...|.:.|
Zfish   596 LMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITM-- 658

  Fly   526 STVMHVKNLFGLPV-----------SEANQTGNYGLNAFIFLNLGVFSTLLWSTTLGFFARRSVG 579
                      ||||           :....:.|....|.:.|.|.:...::......:...:.:|
Zfish   659 ----------GLPVPWLMFSFFHSFAPVPVSSNGLFCAIVLLFLMLLFVIISIAACKWRMNKVLG 713

  Fly   580 IFSIVFYCIYLLFAILIHRKVI 601
            ....:.|.::|:.::::..::|
Zfish   714 FTMFILYFVFLVLSVMLEDRII 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	126/661 (19%)
		Na_Ca_ex	85..219	CDD:279963	36/140 (26%)
		Na_Ca_ex	448..595	CDD:279963	32/157 (20%)
slc24a1	XP_009291877.2	Na_Ca_ex	<112..741	CDD:332332	127/672 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910