Protein Alignment CG12376 and slc24a3

DIOPT Version :10

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_685302.4
• Gene: slc24a3 / 557196
• ZFINID: ZDB-GENE-090312-67
• Length: 660
• Species: Danio rerio
• Alignment Length: 654
• Identity: 137/654 - (20%)
• Similarity: 237/654 - (36%)
• Gaps: 203/654 - (31%)

  Fly    62 DLNC----VNEFEQVIF---------LALFMGLC--YEILVLLIHVCNKYYSPALKAVSRFLCMN 111
            |.||    ::||...||         :||.: ||  |....|.: ||:.|:.|:|:.:...|.::
Zfish    99 DKNCTPPGIHEFPDDIFTQQERLEGAVALHV-LCAMYMFYALAL-VCDDYFVPSLEKICERLHLS 161

  Fly   112 EHVAGVTLLAFGNSSADLFSNLASV---NANVPVFANSLAAALF-VSMVSGGLICYTS-PFKMNA 171
            |.|||.|.:|.|:|:.:||:::..|   ..:|.| ...:.:|:| :..:.|....:|: ..:::.
Zfish   162 EDVAGATFMAAGSSAPELFTSVIGVFITKGDVGV-GTIVGSAVFNILCIIGVCGIFTAQAVRLSC 225

  Fly   172 YESVRDILFLIFGSMLLQYFLASSAHV--PETSFIVMFLVYIFYILVNVVDVYLIRRALK----- 229
            :..:||..:.......|..|:......  .....||::||||..:..|...|:.|.|..|
Zfish   226 WTLMRDSTYYTIAVATLIVFIYDEKVTWWESLILIVLYLVYILIMKFNSRVVHFIERRKKNPANL 290

  Fly   230 ----TTNAQID--------------------ALLVGEM-----------------------TPEK 247
                .:|..||                    .|:|.|:                       :|..
Zfish   291 GNGTASNTDIDDGCDATVVLLKKANFHRKPSVLMVDELLSAYPHQLTFSEAGMRIMITSHFSPRT 355

  Fly   248 R----KRLSELERNQAIYTR----DMEVEI-------FERTNSGPNINKIRYTTLRMGRSTRISL 297
            |    .|:...||.:.|.:|    |.||.:       .|...:||
Zfish   356 RLTMASRMLITERQRLINSRFSNGDSEVTVKMPGKRGVENGLAGP-------------------- 400

  Fly   298 DRKATRMVLHNRAL-GRNWGLF-KDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPL 360
                      :|.| ||..|.. .|...|....:.|...:.|.....
Zfish   401 ----------DRGLNGRKGGHHDDDRGGAEAGTDTENENEDNENNEN------------------ 437

  Fly   361 VDYELDKHGWNK----LLNCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPITV 421
             |.|.::...|:    ...|      |...|..:|.||:      |
Zfish   438 -DEEEEEEDENEGPYVPFRC------PGGGINKLKWLLA------W------------------- 470

  Fly   422 PIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKA 486
            |:::.:|........|.:...:.|..::.::::.|.....: .::.|||:.:.:.|..||.|..|
Zfish   471 PLSMLLFFTVPNSANPRWERWYMVSFISSTIWIAFFSYIMV-WMVTVIGYTMGIPDVIMGITFLA 534

  Fly   487 CTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLPVSEANQTGNYG-- 549
            ...|:...:|::.:|..|...||.:::||...|.:::.          .|||.:......|||
Zfish   535 AGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIG----------LGLPWALQTLAINYGST 589

  Fly   550 --LNA--FIFLNLGVFSTLLWSTTLGFFAR-----RSVGIFSIVFYCIYLLFAILIHRKVIHSFS 605
              ||:  .|| ::|:....::.|.||....     :.:|...::.|.::|.|:|||... |.:|
Zfish   590 IHLNSKGLIF-SVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLCFSILIEFN-IFTF- 651

  Fly   606 VDLP 609
            |:||
Zfish   652 VNLP 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	128/635 (20%)
slc24a3	XP_685302.4	2A1904	<96..650	CDD:273344	133/646 (21%)