Protein Alignment CG12376 and slc24a4a

DIOPT Version :9

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_005158898.1
• Gene: slc24a4a / 550467
• ZFINID: ZDB-GENE-050417-291
• Length: 621
• Species: Danio rerio
• Alignment Length: 655
• Identity: 140/655 - (21%)
• Similarity: 246/655 - (37%)
• Gaps: 191/655 - (29%)

  Fly    39 FVASAKDCNRSTNVLPYMRIMA-----------CDLNCVNEFEQVIF-----------LALFMGL 81
            |.||:....|        |:||           |....::||.:.:|           |.:|..|
Zfish    69 FAASSDRLGR--------RLMATVGDNETQEKNCTAPAIHEFPEDLFTNQQRSQGAVLLHIFAAL 125

  Fly    82 CYEILVLLIHVCNKYYSPALKAVSRFLCMNEHVAGVTLLAFGNSSADLFSNLASV---NANVPVF 143
             |..|.|.| ||:.|:..:|:.:...|.::|.|||.|.:|.|:|:.:||:::..|   :.:|.|
Zfish   126 -YMFLALAI-VCDDYFVTSLEKICEKLHLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGV- 187

  Fly   144 ANSLAAALF-------VSMVSGGLICYTSPFKMNAYESVRDILFLIFGSMLLQYFLASSAHVPET 201
            ...:.:|:|       |..:..|.:.:     :..|...||..:.|...:.|..|:... .:...
Zfish   188 GTIVGSAVFNILCIIGVCGIFAGQVVF-----LTKYAVFRDSSYYIISVIALIVFIYDD-EILWW 246

  Fly   202 SFIVMFLVYIFYILV-----NVVDVYLIRRALKTTNAQIDALLVGEMTP-----------EKRKR 250
            ..:|:.::|:.||:|     ::.:::..:...:.||..   .:..||.|           .....
Zfish   247 ESLVLIVMYLGYIIVMKFNTSLQNLFNGKEDKRVTNGN---AVSSEMEPGNDCFEQFWDDPSWPL 308

  Fly   251 LSELERNQAIYTRDMEVEIFERTNSGPNINKIRYTTLRM------GRSTRISLDRKATRMVLHNR 309
            |:.::.|: ||||...|.:.|..||.|...:.....||:      |..||:   |.|:|::::.:
Zfish   309 LAPVKPNK-IYTRGSVVMVDEMMNSSPPHYRFPEAGLRVMITNHFGPKTRL---RMASRLIINEQ 369

  Fly   310 ------ALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKH 368
                  |.|.:..|..|.       ..:....||:                      .:.:|.:.
Zfish   370 QRLVKSANGVDSVLVSDQ-------KADTMENGNV----------------------AEDKLSEE 405

  Fly   369 GWNKLLNCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPITVPIAVFMFIQSRT 433
            ..|:    |.....|..::..:|..:|      |                   ||::.::
Zfish   406 QENE----ISPFRLPEGAMDTVKFFIS------W-------------------PISLLLY----- 436

  Fly   434 DVPPFYHSVFTVMNLTG---------SMFMIFICATEIDKVL----EVIGHILKVEDDFMGATVK 485
                     ||:.|...         |.|:..:.......:|    .::|:.|.:.|..||.|..
Zfish   437 ---------FTIPNCAKKRWECCFMLSFFLSTVWIAAFSYILVWMVTIVGYTLGIPDVIMGITFL 492

  Fly   486 ACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLPVSEANQTGNYGL 550
            |...|:...||::.:|..|...||.::.||...|.:::.          .|:|........|||.
Zfish   493 AAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVG----------LGVPWGIQTMAVNYGS 547

  Fly   551 NAFIFLNLGVFSTLLW-----STTLGFFARR-----SVGIFSIVFYCIYLLFAILIHRKVIHSFS 605
            ...|.....|:|.:|.     .|.||....|     .:||:.:|.|.|:|.|:|:|...|. :|
Zfish   548 VVKINSRGLVYSVVLLLGSVALTVLGIHVNRWRLDLRLGIYVLVLYAIFLTFSIMIEYNVF-TF- 610

  Fly   606 VDLPV 610
            |:||:
Zfish   611 VNLPM 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	132/635 (21%)
		Na_Ca_ex	85..219	CDD:279963	36/148 (24%)
		Na_Ca_ex	448..595	CDD:279963	40/169 (24%)
slc24a4a	XP_005158898.1	TIGR00367	119..596	CDD:273039	119/574 (21%)
		Na_Ca_ex	120..262	CDD:279963	38/150 (25%)
		Na_Ca_ex	451..602	CDD:279963	40/160 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810