Protein Alignment CG12376 and CG13223

DIOPT Version :9

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: NP_610656.1
• Gene: CG13223 / 36190
• FlyBaseID: FBgn0033599
• Length: 527
• Species: Drosophila melanogaster
• Alignment Length: 580
• Identity: 153/580 - (26%)
• Similarity: 267/580 - (46%)
• Gaps: 69/580 - (11%)

  Fly    35 ERCAFVASAKDCNRSTNVLPYMRIMACDL---NCVNEFEQVIFLALFMGLCYEILVLLIHVCNKY 96
            ::|.||.:..||..:.|:..|:....|.:   |..|.|..|  |.:|:...|...::.|.:.| |
  Fly     9 QKCKFVQTTPDCLINMNLFNYLGWHYCKVDVRNSFNSFWSV--LGMFLITIYVFWMMQITIKN-Y 70

  Fly    97 YSPALKAVSRFLCMNEHVAGVTLLAFGNSSADLFSNLAS-VNANVPVFANSLAAALFVSMVSGGL 160
            :.|.|..::..|.|||..||||:||..|.|.|.|:.:|| |..:...|.:.::.|:|:.:...||
  Fly    71 FCPTLMVIADLLRMNESTAGVTVLAIANGSPDFFTAIASRVQTSKHSFLSCMSQAMFLHIFVAGL 135

  Fly   161 ICYTSPFKMNAYESVRDILFLIFGSMLLQYFLASSAHVPETSFIVMFLVYIFYILVNVVDVY-LI 224
            :..|.||.|.|...:||..||...::.:.|.......:...:.:....:::.|::|.:||.: ||
  Fly   136 VILTKPFNMRANTYLRDFGFLFLNTVYMDYIHKRPKGISWLAALPSAFIFVGYVVVAIVDQHLLI 200

  Fly   225 RRALKTTNAQI---DALLVGEMTPEKRKRLSELERNQAIYTRDMEVEIFERTNSGPNINKIRYTT 286
            .|..|....|:   :||.:.|:.|:|...|...|
  Fly   201 ARIQKMEQRQLNVAEALQLEELKPQKEMPLKRQE------------------------------- 234

  Fly   287 LRMGRSTRISLDRKATRMVLHNRALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAV 351
                      :||.:   :.|.   .||..:|:..:..:...:.:::.:|..:.:.:::.|.|..
  Fly   235 ----------IDRPS---IGHG---SRNKRIFRQFWNTVAEFDKDRFHRGTFLVKLYLIVKQPID 283

  Fly   352 IICCIYIPLVDYELDKHGWNKLLNCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYS 416
            ::..|.||.||.|..::||:|||..|||:|.|...     |.:..||.|:     ...|:| |.:
  Fly   284 MLLRILIPKVDMEAPQYGWSKLLFNIQVVLVPTYI-----AYIIVRGYSI-----AGLAVY-MIA 337

  Fly   417 LPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMG 481
            |.:.:|:|..:|..:|||.||.:....:.:....::|:||...||::.:...:..||:|..:|..
  Fly   338 LILMIPVATLIFFLTRTDTPPIFFRFTSGVGFMAAVFLIFCLTTEVNAMFFTMATILQVSQEFSL 402

  Fly   482 ATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLPVSEANQTG 546
            ||......|...|:||:::|..|:||||..:....|.|...:..:..:.|.:....|.:.....|
  Fly   403 ATAICWALSSNDLVANLSLAHQGWPRMAMTATFSAPVFASFVFLALPLVVNSFVNAPGNIFPTEG 467

  Fly   547 NYGLNAFIFLNLGVFSTLLWSTTLGFFARRSVGIFSIVFYCIYLLFAILIHRKVIHSFSV 606
            .:|....|||.:|:..::|...|..|..||:.|...:.:|..::...||:.:.|||::.|
  Fly   468 GFGETVCIFLEVGMGFSMLSVLTTNFKLRRACGFLLVSYYIFFVGVLILLEKGVIHAYGV 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	147/564 (26%)
		Na_Ca_ex	85..219	CDD:279963	39/134 (29%)
		Na_Ca_ex	448..595	CDD:279963	38/146 (26%)
CG13223	NP_610656.1	Na_Ca_ex	45..194	CDD:279963	44/151 (29%)
		Na_Ca_ex	365..516	CDD:279963	38/150 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450102
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1872
Isobase	1	0.950	-	0	Normalized mean entropy	S4675
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		otm26516
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	P	PTHR12266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.780