Protein Alignment CG12376 and Slc24a5

DIOPT Version :9

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_038960915.1
• Gene: Slc24a5 / 311387
• RGDID: 1310565
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 569
• Identity: 113/569 - (19%)
• Similarity: 194/569 - (34%)
• Gaps: 186/569 - (32%)

  Fly    72 VIF--LALFMGLCYEILVLLIHVCNKYYSPALKAVSRFLCMNEHVAGVTLLAFGNSSADLFSNLA 134
            ||:  :.|:|.:...|      ||:||:.|:|:.:|..|.:::.|||.|.:|.|:|:.:|
  Rat    72 VIYFLITLYMFMAVSI------VCDKYFLPSLEIISDSLGLSQDVAGATFMAAGSSAPEL----- 125

  Fly   135 SVNANVPVFANS--------------------LAAALFVSMVSGGLICYTSPFKMNAYE-SVRDI 178
             |.|.:.||...                    .|..|..:||| .|.|:........|. ||..:
  Rat   126 -VTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMVS-TLSCWPLFRDCAVYAVSVGAV 188

  Fly   179 LFLIFGSMLLQYFLASSAHVPETSFIVMFLVYIFYILVNVVDVYLIRRALKTTNAQIDALLVGEM 243
            ..:||.:.:..|..|           ::.|:|..|:|:...|..:.|...||..         ..
  Rat   189 FGIIFDNRVYWYEGA-----------LLLLIYGLYVLLLCFDTTISRYVTKTCR---------PC 233

  Fly   244 TPEKRKRLSELERNQAIYTRDMEVEIF----ERTNSGPNINKIRYTTLRMGRSTRISLDRKATRM 304
            .|...|.:.|....|.:...:.|.:|:    .||:||.......|:.|.:.
  Rat   234 CPCLAKAMEERSEQQTLLGWENESQIYIRRQSRTDSGIFQEDSGYSQLSLS-------------- 284

  Fly   305 VLHNRALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKHG 369
             ||        ||.:   ::..|.:.....:.: ::|.|.:..:|.:.:..:..|
  Rat   285 -LH--------GLSQ---VSEDPPSVFSMPEAD-LRRIFWVLSLPVITLLALTTP---------- 326

  Fly   370 WNKLLNCIQVMLNPAMSIMAIKALLSSRGNSLW--YVAMGEEAIYAMYSLPITVPIAVFMFIQSR 432
                 :|                     ...||  |..                 |..||
  Rat   327 -----DC---------------------RRKLWKNYFV-----------------ITFFM----- 343

  Fly   433 TDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIAN 497
               ..|:.|.||.:       :::        ::.:.|..|.:.|..||.|:.|...|:...:|:
  Rat   344 ---SAFWISAFTYV-------LVW--------MVTITGETLGIPDTVMGLTLLAAGTSIPDTVAS 390

  Fly   498 VAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLP---------VSEANQTGNYGLNAF 553
            |.:|..|...||.::.:|...|.::           ..|||         .|...:..:.||...
  Rat   391 VLVARKGKGDMAISNIVGSNVFDML-----------CLGLPWFIKTAFTNASAPIEVNSKGLTYI 444

  Fly   554 -IFLNLGVFSTLLWSTTLGFFARRSVGIFSIVFYCIYLLFAILIHRKVI 601
             |.||:.:|...|.....|:...|.:|:..:|.|......::|....:|
  Rat   445 TISLNISIFLLFLAVHFNGWKLDRKLGVVCLVSYLGLATLSVLYELGII 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	111/558 (20%)
		Na_Ca_ex	85..219	CDD:279963	39/154 (25%)
		Na_Ca_ex	448..595	CDD:279963	32/156 (21%)
Slc24a5	XP_038960915.1	2A1904	<20..>241	CDD:273344	49/201 (24%)
		2A1904	<293..493	CDD:273344	49/287 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810