Protein Alignment CG12376 and ncx-9

DIOPT Version :10

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: NP_504342.2
• Gene: ncx-9 / 182576
• WormBaseID: WBGene00003574
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 717
• Identity: 160/717 - (22%)
• Similarity: 286/717 - (39%)
• Gaps: 172/717 - (23%)

  Fly    15 EFDNFWDTVSCYAAN-----TFPF------------------EERCAFVASAKDCNRSTNVLPYM 56
            |:|..:|..|..:.|     .|||                  ||:|.::...:|.......|.:.
 Worm    24 EYDQSYDYPSPGSTNFSIYDGFPFDEEMCSSEECLIDKSWTSEEKCEYIKCNQDSCEGGGYLTWS 88

  Fly    57 RIMACDLNCVNEFEQVIFLALFMGLCYEIL--VLLIHVCNKYYSPALKAVSRFLCMNEHVAGVTL 119
            ..:.|..|.     .|..:.:.:|:.|.|:  |::..:.:.::.||:..:...|.|:|.:||||.
 Worm    89 HYVKCQYNI-----GVRVILIILGILYLIILFVIMSSIADDFFCPAISGIVSHLRMSESIAGVTF 148

  Fly   120 LAFGNSSADLFSNLASVNANVP------VFANSLAAALFVSMVSGGLICYTSPFKMNAYESVRDI 178
            |||||.:.|:||:::|| ...|      ...:....::||:.|...:|.:|..||:....::||:
 Worm   149 LAFGNGAPDVFSSISSV-LTTPKPKADLALGDLFGTSIFVTTVVLAIIIFTKSFKVAIIPTLRDL 212

  Fly   179 LF----LIFGSMLLQYFLASSAHVPETSFIVMFLVYIF-YILVNVVDVYLIRRALKTTNAQIDAL 238
            :|    |.|.......|......:|.| |:.::.||:. .|::.:...:..:|.||..|.:::..
 Worm   213 IFYMTTLAFIVFCFLKFDKIEVWMPAT-FLGIYGVYVVTVIILGIYRTHRKKRNLKKKNKELEDF 276

  Fly   239 L-----VGEMTP--------EKRKRLSELERNQAIYTRDME----VEIFERTNSGPNINK-IRYT 285
            |     ....||        |:...:|.|......|::.::    ..:...||:..|.|| .:..
 Worm   277 LSRPSSAASTTPIFGAMKLKEETISVSALFHFMIGYSQFIKNLTRANLKRTTNNNNNDNKNEKRG 341

  Fly   286 TLRMGRSTRISL--DRKATRMVLHNR--------------------------------------- 309
            .:.:|.|...|:  :||.:.:...|.
 Worm   342 IVNLGFSEPYSIPSERKISTIFKQNTFETDLESLESLADLDGSDDEGREEKFGYAHHTVFTSHDQ 406

  Fly   310 -------------ALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLV 361
                         ...|:|....|||..|:     .|...:......:..||..||   ..:|:.
 Worm   407 ISLVASEIEEIEITTWRSWDWVWDLFNHLK-----SWPSRDEFSEMNIFIKIVTVI---KVVPVF 463

  Fly   362 DYEL----DKHGWNK---LLNC---IQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAI---YA 413
            .::|    ::..|.|   :|:|   ||..|. ::.|:.:|....|.|  ||...:|..||   .|
 Worm   464 FFKLTVPSNEMSWCKPLFILHCFASIQFALF-SIQIITLKPFDGSPG--LWLYGLGFSAILAMVA 525

  Fly   414 MYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDD 478
            ||.||:             :....:|..:::.:....|:..|:..:.||..|:.:||.:..:..:
 Worm   526 MYFLPL-------------SKEQKYYKEIYSYLGFLMSIAWIYATSNEIVSVVTMIGVVTGLSME 577

  Fly   479 FMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLPVSEAN 543
            .:|.|:.|.:..:|.::|::|:...|||:||.|:|||||.|.:::.          ||||.:.|.
 Worm   578 LLGLTIMAWSNCIGDIVADIAVVKQGYPKMAMAAAIGGPLFNLLIG----------FGLPFTIAA 632

  Fly   544 QTGN---------YGLNAFIFLNLGVFSTLLWSTTLGFFARRSVGIFSIVFYCIYLLFAILIHRK 599
            ..|.         |.| ..:||.:.:.:|.:......|..||...:..|..:.::|:|..|....
 Worm   633 AQGKEMELLINPVYRL-LMLFLGISLVTTFVALFIQRFTVRRPHAVLLIFIFVVFLIFICLAEFH 696

  Fly   600 VI 601
            |:
 Worm   697 VL 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	150/683 (22%)
ncx-9	NP_504342.2	PLN03151	68..689	CDD:215604	147/662 (22%)