Protein Alignment CG12376 and ncx-4

DIOPT Version :9

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: NP_001040663.1
• Gene: ncx-4 / 172834
• WormBaseID: WBGene00003569
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 587
• Identity: 126/587 - (21%)
• Similarity: 242/587 - (41%)
• Gaps: 113/587 - (19%)

  Fly    46 CNRSTNVLPYMRIMACDLNCVNEF---------EQVIFLALFM-GLCYEILVLLIHVCNKYYSPA 100
            ||||      :...|.|:|...:|         .|..|:.|.| ||.|..:.|.| ||::::.|:
 Worm    70 CNRS------LAPPAPDVNDDGQFPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAI-VCDEFFVPS 127

  Fly   101 LKAVSRFLCMNEHVAGVTLLAFGNSSADLFSNLASVNANVPVFANSLAAALFVSMVSGGLICY-- 163
            |..::..|.:::.|||.|.:|.|.|:.:.|:::..|.    :..|::.....|...:..::|.
 Worm   128 LDVLTEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVF----IAQNNVGIGTIVGSATFNILCVLA 188

  Fly   164 ------TSPFKMNAYESVRDI-LFLIFGSMLLQYFLASSAHVPETSFIVMFLVYIFYILVNVVDV 221
                  .|...:..:...||: ::::..:||:.:|:......||.  :.||.:||.|..|
 Worm   189 FCTLFSKSILDLTWWPLFRDVSIYMLALAMLVFFFMDEMITFPEA--LAMFSIYIVYCTV----- 246

  Fly   222 YLIRRALKTTNAQIDALLVGEMTPEKRKRLSELERNQAIYTRDMEVEIFERTNSGPNINKIRYTT 286
                   ...|.|::.|:         |:.|:.|...|..|:.:..:: ...|:..::.::..:.
 Worm   247 -------MKFNGQLEQLV---------KKGSDSEEASAHETQKLAADV-PHNNNNNDLAQLEGSE 294

  Fly   287 LRMGRSTRISLDRKATRMVLHNRALGRNWGLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAV 351
            ||     |.|..|:.:..:||:..:.|| |:.:.:...|..:..:.....:...|:
 Worm   295 LR-----RRSSARRQSVPILHSGTMFRN-GIMQLMNQTLEQLPEDSEEDDSSRSRS--------- 344

  Fly   352 IICCIYIPLVDYELDKHGWNKLLNCIQVMLNPAMS-IMAIKALLSSRG----NSLWYVAMGEEAI 411
                      :..::.|..:: ||..|.|.:...| |..||:||..:.    :..|.....:...
 Worm   345 ----------NVNIESHDMHR-LNVNQSMPDRRSSQIEEIKSLLEEQEEKPLDMTWPETWVKRLT 398

  Fly   412 YAMYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMF---MIFICATEIDKVLEVIGHIL 473
            |.:.: |:.:|:.|.:....::.....|.:.|.:..|..:.|   |::...|        ||...
 Worm   399 YVLLA-PVVIPMWVTIPDVRKSHNRGLYPATFIISILWIAFFSYLMVWWANT--------IGETF 454

  Fly   474 KVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSAS-------TVMHV 531
            .:..:.:|.|:.|...|:..||.:|.:|..|...||.:|::|...|.|.:...       .:.::
 Worm   455 VIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPWLLYFLIEYI 519

  Fly   532 KN----LFGLPVSEANQTGNYGLNAFIFLNLGVFSTLLWSTTLGFFARRSVGIFSIVFYCIYLLF 592
            |:    |..:.||......:.|: .||.|.:.||:..|    .|:...:..||..||.|..:.:|
 Worm   520 KHPNEPLSPISVSSKGLLCSVGM-LFIMLIVLVFAIFL----SGWKMNKIFGILMIVSYVFFCVF 579

  Fly   593 AI 594
            ::
 Worm   580 SV 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	125/583 (21%)
		Na_Ca_ex	85..219	CDD:279963	33/142 (23%)
		Na_Ca_ex	448..595	CDD:279963	39/161 (24%)
ncx-4	NP_001040663.1	2A1904	<48..594	CDD:273344	126/587 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910