Protein Alignment CG12376 and slc24a4

DIOPT Version :9

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_002933272.2
• Gene: slc24a4 / 100489343
• XenbaseID: XB-GENE-478288
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 139/635 - (21%)
• Similarity: 231/635 - (36%)
• Gaps: 200/635 - (31%)

  Fly    64 NC----VNEFEQVIF--------LALFMGLC--YEILVLLIHVCNKYYSPALKAVSRFLCMNEHV 114
            ||    :|||...:|        ..||...|  |....|.| ||:.::.|:|:.:...|.::|.|
 Frog    83 NCTEPAINEFPDDLFSIKERQRGAVLFHIFCALYMFYALAI-VCDDFFVPSLEKICEKLHLSEDV 146

  Fly   115 AGVTLLAFGNSSADLFSNLASV---NANVPVFANSLAAALF-------VSMVSGGLICYTSPFKM 169
            ||.|.:|.|:|:.:||:::..|   :.:|.| ...:.:|:|       |..|..|.:     .::
 Frog   147 AGATFMAAGSSTPELFASVIGVFITHGDVGV-GTIVGSAVFNILCIIGVCGVFAGQV-----VRL 205

  Fly   170 NAYESVRDILFLIFGSMLLQYFLASSAHVPETSFIVMFLVYIFYILV---------------NVV 219
            ..:...||.::.|...:.|..|:.....|...| :::.::|.||||:               ||.
 Frog   206 TWWSLFRDSMYYIISILALIIFIYDEIIVWWES-LILIVMYFFYILIMKYNTKMQRLFTIKKNVG 269

  Fly   220 DVYLIRRALKTTNAQIDALLVGEMTPEKRKRLSELERNQAIYTRDMEVEIFERTNSGPNINKIRY 284
            :...:...|:..|...|.:......|    .|.:::.:|..|.|:..|.:.|...|.|  .|.|:
 Frog   270 NGCPVGSELQDGNVYSDFVCDDPSVP----LLWKVKASQQYYNRNSVVMVDEIICSSP--PKYRF 328

  Fly   285 --------TTLRMGRSTRISLDRKATRMVLHNR-------------------ALGRNWGLFKD-- 320
                    .|.:....||:   |.|:|::::.|                   .|..|.||..|
 Frog   329 PEAGLRIMITNKFPPRTRL---RMASRLIINERQRLLHSANGTSTTTLDGKQELLENGGLHVDKA 390

  Fly   321 -----------LFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKHGWNKLL 374
                       |.....|..|     .||.|.||...     :||.:|..:.:  ..|..|....
 Frog   391 DDYQEENEANYLVPFSVPSGC-----ANIFKWAFSWP-----LICILYFTIPN--CSKPRWENFF 443

  Fly   375 NCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPITVPIAVFMFIQSRTDVPPFY 439
                              :|:...::||                    ||:|.:|
 Frog   444 ------------------MLTFITSTLW--------------------IAIFSYI---------- 460

  Fly   440 HSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHG 504
                          |::        ::.|||:.|.:.|..||.|..|...|:...:|::.:|..|
 Frog   461 --------------MVW--------MVTVIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG 503

  Fly   505 YPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLPVSEANQTGNYGLNAFIFLNLGVFST--LLWS 567
            ...||.:::||...|.:::.          .|:|........|||....|.....|:|.  ||.|
 Frog   504 LGDMAVSNSIGSNVFDILVG----------LGVPWGLQTMIINYGSTVKINSKGLVYSVILLLGS 558

  Fly   568 TTL---GFFAR-----RSVGIFSIVFYCIYLLFAILIHRKVIHSFSVDLP 609
            ..|   |.:..     :..|.:.:..|.|:|.|::||...|. :| |:||
 Frog   559 VALTVGGIYVNKWKLDKKFGFYVLFLYAIFLCFSVLIEYNVF-TF-VNLP 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	131/616 (21%)
		Na_Ca_ex	85..219	CDD:279963	38/158 (24%)
		Na_Ca_ex	448..595	CDD:279963	37/156 (24%)
slc24a4	XP_002933272.2	2A1904	<91..596	CDD:273344	130/613 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1775
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940