Protein Alignment CG12376 and slc24a4b

DIOPT Version :10

• Sequence 1: NP_610405.3
• Gene: CG12376 / 35857
• FlyBaseID: FBgn0033323
• Length: 617
• Species: Drosophila melanogaster
• Sequence 2: XP_002665845.2
• Gene: slc24a4b / 100334346
• ZFINID: ZDB-GENE-081031-75
• Length: 636
• Species: Danio rerio
• Alignment Length: 635
• Identity: 145/635 - (22%)
• Similarity: 231/635 - (36%)
• Gaps: 219/635 - (34%)

  Fly    64 NC----VNEFEQVIF----------LALFMGLCYEILVLLIHVCNKYYSPALKAVSRFLCMNEHV 114
            ||    ::||...:|          |...:...|..|.|.| ||:.|:..:|:.:...|.::|.|
Zfish   129 NCTEPAIHEFPDDVFTNAERKSGAVLLHIIAALYMFLALAI-VCDDYFVTSLEKICEKLNLSEDV 192

  Fly   115 AGVTLLAFGNSSADLFSNLASV---NANVPVFANSLAAALFVSMVSGGLICYTSPFKMNAYESV- 175
            ||.|.:|.|:|:.:||:::..|   :.:|.| ...:.:|:|      .::|......:.|.:.|
Zfish   193 AGATFMAAGSSAPELFASVIGVFITHGDVGV-GTIVGSAVF------NILCIIGVCGIFAGQVVL 250

  Fly   176 -------RDILFLIFGSMLLQYFLASSAHVPETSFIVMFLVYIFYILV----NVVDVYLIRRALK 229
                   ||..|.|...:.|..|:.....|...| :|:.::|..|||:    :.:..:..|:..|
Zfish   251 LTWWAVFRDSFFYILSVVALIVFIYDEKIVWWES-LVLVVMYACYILIMKFNSRLQKFFTRKGNK 314

  Fly   230 TT---NAQIDALLVGEMTPEKRKRLSELE--RNQAIYTRDMEVEIFERTNSGPNINKIRYTTLRM 289
            ..   ||...               ||||  :...||:|...|.:.|..|:.|...:.....||:
Zfish   315 NVANGNAAAG---------------SELEDVKTSKIYSRGSVVMVDEIINASPPNYRFPEAGLRV 364

  Fly   290 ------GRSTRISLDRKATRMVLHNR------ALG------------RNWGLFKD---------L 321
                  |..||:   |.|:|:::..|      |.|            .|..:.:|         |
Zfish   365 MVTNHFGPKTRL---RMASRLIITERQRLVQSANGVETAVVDGKPDIENGNVPEDKSTEEKESEL 426

  Fly   322 FIALR-PINC---EKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKHGWNKLLNCIQVMLN 382
            ....| |..|   .||           |...|.::|....||               ||
Zfish   427 TTPFRLPDGCMNRTKW-----------LISWPLLLILFFTIP---------------NC------ 459

  Fly   383 PAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMN 447
                           ..|.|      |..:.:..:..||.||||
Zfish   460 ---------------AKSRW------EKYFMLSFILSTVWIAVF--------------------- 482

  Fly   448 LTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYAS 512
               |.||::        ::.:||:.|.:.|..||.|..|...|:...||::.:|..|...||.::
Zfish   483 ---SYFMVW--------MVTIIGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSN 536

  Fly   513 AIGGPFFTVVMSASTVMHVKNLFGLPVSEANQT--GNYGLNAFIFLNLGVFSTLLWS-------- 567
            .||...|.:            |.||.|..|.||  .|||  :.:.:|   ...||:|
Zfish   537 TIGSNVFDI------------LVGLGVPWALQTMAVNYG--SVVMIN---SRGLLYSVVLLLGSV 584

  Fly   568 --TTLGFFARR-----SVGIFSIVFYCIYLLFAILIHRKVIHSFSVDLPV 610
              |.||.....     .:|::.::.|.::|.|:|:|...|. :| |:||:
Zfish   585 ALTILGIHLNHWKLDFKLGVYVLLLYAVFLCFSIMIEYNVF-TF-VNLPM 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12376	NP_610405.3	PLN03151	33..592	CDD:215604	137/615 (22%)
slc24a4b	XP_002665845.2	2A1904	<112..621	CDD:273344	139/620 (22%)