DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8584 and TIMM50

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001001563.2	Gene:	TIMM50 / 92609	HGNCID:	23656	Length:	353	Species:	Homo sapiens

Alignment Length:	173	Identity:	47/173 - (27%)
Similarity:	84/173 - (48%)	Gaps:	20/173 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 LPE-----HAQPDYVLNISIDG--MEP-----IVFRVFKRPHVDEFLDFVSKWYDLVIYTASLEV 177
            ||:     :.||.|.|.:.:.|  :.|     ..:|..|||.::.....::..|::||:|:...:
Human   135 LPDPLQEPYYQPPYTLVLELTGVLLHPEWSLATGWRFKKRPGIETLFQQLAPLYEIVIFTSETGM 199

  Fly   178 YAAQVVDHLDAGRGLITRRFYRQHCRASSPMVSKDLTLVTPDMSGVLIIDNSPYAYRDFPDNAIP 242
            .|..::|.:|. .|.|:.|.:|...|.......||::.:..|.:.|:::|....|:|..|.|.:.
Human   200 TAFPLIDSVDP-HGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNGVA 263

  Fly   243 IKTFIYDPDDTELLKMLPFLD--ALRFTKDVRSILGRRVIRHY 283
            ::.:..:.||..||.:..||.  ||...:|||::|     .||
Human   264 LRPWDGNSDDRVLLDLSAFLKTIALNGVEDVRTVL-----EHY 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	41/158 (26%)
TIMM50	NP_001001563.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	25..60
TIMM50	NP_001001563.2	HAD_FCP1-like	147..262	CDD:319823	29/115 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910