Protein Alignment CG8584 and NEM1

DIOPT Version :10

• Sequence 1: NP_610404.1
• Gene: CG8584 / 35856
• FlyBaseID: FBgn0033322
• Length: 293
• Species: Drosophila melanogaster
• Sequence 2: NP_011867.1
• Gene: NEM1 / 856393
• SGDID: S000001046
• Length: 446
• Species: Saccharomyces cerevisiae
• Alignment Length: 321
• Identity: 100/321 - (31%)
• Similarity: 158/321 - (49%)
• Gaps: 68/321 - (21%)

  Fly     3 SQLPAQSADL----DKLAPSGQFAVAVVSNLQRSRSSSDRRGLVLILLSSD--LGTYIRRLLARV 61
            ::||..|:::    :|..|.......:...::...::||.     |:|..|  .|:.:|
Yeast   145 NELPVSSSNINDSSEKTNPKNCNLNTIPEAVEDDLNASDE-----IILQRDNVKGSLLR------ 198

  Fly    62 AEKACTILRTYLGLSYREVSVSQDMAHRLAVVG-----------------------RKTLVLDLD 103
            |:...:..|:|   |..|:|:|...:.. .|.|                       :|.||:|||
Yeast   199 AQSVKSRPRSY---SKSELSLSNHSSSN-TVFGTKRMGRFLFPKKLIPKSVLNTQKKKKLVIDLD 259

  Fly   104 ETLVHSCYLDPDTHDNVGCSQLPEHAQPDYVLNISIDGMEPIVFRVFKRPHVDEFLDFVSKWYDL 168
            |||:||.... .||.|.....|.|       :...:.|:..:.| :.|||:.|.||..|||||||
Yeast   260 ETLIHSASRS-TTHSNSSQGHLVE-------VKFGLSGIRTLYF-IHKRPYCDLFLTKVSKWYDL 315

  Fly   169 VIYTASLEVYAAQVVDHLDAG-RGLITRRFYRQHCRASSPM-VSKDLTLV----------TPDMS 221
            :|:|||::.||..|:|.|::. ....::|:||..|.....: ..|||::|          :..:.
Yeast   316 IIFTASMKEYADPVIDWLESSFPSSFSKRYYRSDCVLRDGVGYIKDLSIVKDSEENGKGSSSSLD 380

  Fly   222 GVLIIDNSPYAYRDFPDNAIPIKTFIYDPDDTELLKMLPFLDALRFTKDVRSILGRRVIRH 282
            .|:||||||.:|....||||.::.:|.||.||:||.:||||:|:|::.|||:||   .::|
Yeast   381 DVIIIDNSPVSYAMNVDNAIQVEGWISDPTDTDLLNLLPFLEAMRYSTDVRNIL---ALKH 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	73/186 (39%)
NEM1	NP_011867.1	NIF	252..431	CDD:397254	74/187 (40%)