DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8584 and ctdspla

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	XP_005162767.1	Gene:	ctdspla / 751737	ZFINID:	ZDB-GENE-060825-333	Length:	276	Species:	Danio rerio

Alignment Length:	197	Identity:	71/197 - (36%)
Similarity:	109/197 - (55%)	Gaps:	24/197 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 EVSVSQDMAHRLAVVGRKTLVLDLDETLVHSCYLDPDTHDNVGCSQLPEHAQPDYVLNISIDGME 143
            |||::.        .|:..:|:|||||||||.:              ...:..|:::.:.|||..
Zfish    98 EVSIND--------YGKNCVVIDLDETLVHSSF--------------KPISNADFIVPVEIDGTV 140

  Fly   144 PIVFRVFKRPHVDEFLDFVSKWYDLVIYTASLEVYAAQVVDHLDAGRGLITRRFYRQHCRASSPM 208
            ..|: |.|||||||||..:.:.::.|::||||..||..|.|.||.. |:...|.:|:.|......
Zfish   141 HQVY-VLKRPHVDEFLQKMGEMFECVLFTASLAKYADPVADLLDQW-GVFRARLFRESCVFHRGN 203

  Fly   209 VSKDLTLVTPDMSGVLIIDNSPYAYRDFPDNAIPIKTFIYDPDDTELLKMLPFLDALRFTKDVRS 273
            ..|||:.:..:::.|:|:||||.:|...|:||:|::::..|..|||||.:||..:.|....||.|
Zfish   204 YVKDLSRLGRELNKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLLPLFEGLSRETDVYS 268

  Fly   274 IL 275
            :|
Zfish   269 VL 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	63/174 (36%)
ctdspla	XP_005162767.1	KCNQ2_u3	14..92	CDD:293248
		FCP1	<95..272	CDD:227517	71/197 (36%)
		HIF-SF_euk	106..265	CDD:274055	63/174 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820