DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8584 and ctdspl2a

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001071012.1	Gene:	ctdspl2a / 558181	ZFINID:	ZDB-GENE-061013-647	Length:	469	Species:	Danio rerio

Alignment Length:	189	Identity:	69/189 - (36%)
Similarity:	110/189 - (58%)	Gaps:	20/189 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 TLVLDLDETLVHSCYLDPDTHDNVGCSQLPEHAQPDYVLNISIDGMEPIVFRVF--KRPHVDEFL 159
            :||||||||||| |.|          ::|.:.|....||      .:.::::|:  .||...|||
Zfish   292 SLVLDLDETLVH-CSL----------NELEDAALTFPVL------FQDVIYQVYVRLRPFFREFL 339

  Fly   160 DFVSKWYDLVIYTASLEVYAAQVVDHLDAGRGLITRRFYRQHCRASSPMVSKDLTLVTPDMSGVL 224
            :.:|:.|:::::|||.:|||.::::.||..:.|:..|.:|:||........|||.::..|:|..:
Zfish   340 ERMSQIYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTV 404

  Fly   225 IIDNSPYAYRDFPDNAIPIKTFIYDPDDTELLKMLPFLDAL-RFTKDVRSILGRRVIRH 282
            ||||||.|:.....|.|||:::..|.:|.||||::|||:.| ...:|||..:..|...|
Zfish   405 IIDNSPQAFAYQLSNGIPIESWFVDKNDNELLKLVPFLEKLVELNEDVRPYIRERFRLH 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	64/175 (37%)
ctdspl2a	NP_001071012.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..136
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..209
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	231..250
		HIF-SF_euk	290..445	CDD:274055	63/169 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820