DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8584 and CTDSPL2

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_057480.2	Gene:	CTDSPL2 / 51496	HGNCID:	26936	Length:	466	Species:	Homo sapiens

Alignment Length:	211	Identity:	72/211 - (34%)
Similarity:	118/211 - (55%)	Gaps:	27/211 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 VSQDMAHRLAVVGRKT-------LVLDLDETLVHSCYLDPDTHDNVGCSQLPEHAQPDYVLNISI 139
            ::::..:|...:..||       ||||||||||| |.|          ::|.:.|....||
Human   267 LTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVH-CSL----------NELEDAALTFPVL---- 316

  Fly   140 DGMEPIVFRVF--KRPHVDEFLDFVSKWYDLVIYTASLEVYAAQVVDHLDAGRGLITRRFYRQHC 202
              .:.::::|:  .||...|||:.:|:.|:::::|||.:|||.::::.||..:.|:..|.:|:||
Human   317 --FQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHC 379

  Fly   203 RASSPMVSKDLTLVTPDMSGVLIIDNSPYAYRDFPDNAIPIKTFIYDPDDTELLKMLPFLDAL-R 266
            ........|||.::..|:|..:||||||.|:.....|.|||:::..|.:|.||||::|||:.| .
Human   380 VCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVE 444

  Fly   267 FTKDVRSILGRRVIRH 282
            ..:|||..:..|...|
Human   445 LNEDVRPHIRDRFRLH 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	66/184 (36%)
CTDSPL2	NP_057480.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..140
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	220..240
		HIF-SF_euk	287..448	CDD:274055	64/177 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820