DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8584 and ctdnep1b

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001007441.2	Gene:	ctdnep1b / 492799	ZFINID:	ZDB-GENE-041114-152	Length:	248	Species:	Danio rerio

Alignment Length:	230	Identity:	113/230 - (49%)
Similarity:	148/230 - (64%)	Gaps:	14/230 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 YIRRLLARVAEKACTILRTYLGLSYREVSVSQDMAHRLAVVGRKTLVLDLDETLVHSCYLDPDTH 117
            ||.|...|      ||:: |..:.|..:|:|....:||..|.||.|||||||||:||      .|
Zfish    30 YILRKHIR------TIIQ-YQTVRYDVLSLSPISRNRLNNVKRKILVLDLDETLIHS------HH 81

  Fly   118 DNVGCSQLPEHAQPDYVLNISIDGMEPIVFRVFKRPHVDEFLDFVSKWYDLVIYTASLEVYAAQV 182
            |.|....:.....||::|.:.|| ..|:.|.|.||||||.||:.||:||:||::|||:|:|.:.|
Zfish    82 DGVLRPTVRPGTPPDFILKVVID-KHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAV 145

  Fly   183 VDHLDAGRGLITRRFYRQHCRASSPMVSKDLTLVTPDMSGVLIIDNSPYAYRDFPDNAIPIKTFI 247
            .|.||..:.::.||:|||||...|....|||::|..|:|.|:|:||||.|||..||||||||::.
Zfish   146 ADKLDNNKAILKRRYYRQHCTLDSGSYIKDLSVVHDDLSSVVILDNSPGAYRSHPDNAIPIKSWF 210

  Fly   248 YDPDDTELLKMLPFLDALRFTKDVRSILGRRVIRH 282
            .||.||.||.:||.|||||||.||||:|.|.:.:|
Zfish   211 SDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQH 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	93/174 (53%)
ctdnep1b	NP_001007441.2	HIF-SF_euk	65..233	CDD:274055	93/174 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D468474at33208
OrthoFinder	1	1.000	-	-		FOG0002783
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12210
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1870
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.880