DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8584 and ctdnep1a

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001007310.1	Gene:	ctdnep1a / 492343	ZFINID:	ZDB-GENE-041114-177	Length:	245	Species:	Danio rerio

Alignment Length:	217	Identity:	109/217 - (50%)
Similarity:	142/217 - (65%)	Gaps:	10/217 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LRT---YLGLSYREVSVSQDMAHRLAVVGRKTLVLDLDETLVHSCYLDPDTHDNVGCSQLPEHAQ 130
            |||   |..:.|..:.:|....:||..|.||.|||||||||:||      .||.|....:.....
Zfish    33 LRTIIQYQTVRYDILPLSPISRNRLNAVKRKILVLDLDETLIHS------HHDGVLRPTVRPGTP 91

  Fly   131 PDYVLNISIDGMEPIVFRVFKRPHVDEFLDFVSKWYDLVIYTASLEVYAAQVVDHLDAGRGLITR 195
            ||::|.:.|| ..|:.|.|.||||||.||:.||:||:||::|||:|:|.:.|.|.||..||::.|
Zfish    92 PDFILKVVID-KHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNNRGILKR 155

  Fly   196 RFYRQHCRASSPMVSKDLTLVTPDMSGVLIIDNSPYAYRDFPDNAIPIKTFIYDPDDTELLKMLP 260
            |:|||||........|||::|..|:|.::|:||||.|||..||||||||::..||.||.||.:||
Zfish   156 RYYRQHCTLDLGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLP 220

  Fly   261 FLDALRFTKDVRSILGRRVIRH 282
            .|||||||.||||:|.|.:.:|
Zfish   221 MLDALRFTSDVRSVLSRNLHQH 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	93/174 (53%)
ctdnep1a	NP_001007310.1	HIF-SF_euk	62..230	CDD:274055	93/174 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176152at2759
OrthoFinder	1	1.000	-	-		FOG0002783
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12210
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1870
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.880