DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8584 and timm50

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_956959.1	Gene:	timm50 / 393638	ZFINID:	ZDB-GENE-040426-1618	Length:	387	Species:	Danio rerio

Alignment Length:	181	Identity:	43/181 - (23%)
Similarity:	80/181 - (44%)	Gaps:	33/181 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 TLVLDLDETLVHSCYLDPDTHDNVGCSQLPEHAQPDYVLNISIDGMEPIVFRVFKRPHVDEFLDF 161
            ||||:|.:.|:|                      |::.|...        :|..|||.:|.....
Zfish   184 TLVLELTDVLLH----------------------PEWSLATG--------WRFKKRPGIDYLFQQ 218

  Fly   162 VSKWYDLVIYTASLEVYAAQVVDHLDAGRGLITRRFYRQHCRASSPMVSKDLTLVTPDMSGVLII 226
            ::..|::||:|:...:.|..::|.:|. :|.:..|.:|...|.......||::.:..|.|.|:::
Zfish   219 LAPLYEIVIFTSETGMTAYPLIDSIDP-QGFVMYRLFRDATRYMEGHHVKDVSCLNRDTSKVIVV 282

  Fly   227 DNSPYAYRDFPDNAIPIKTFIYDPDDTELLKMLPFLDALRFT--KDVRSIL 275
            |....|:...|.|.:.:..:..:.:|..|..:..||..:..:  :||||:|
Zfish   283 DCKREAFGLQPFNGLALCKWDGNSEDRTLYDLAAFLKTIATSGVEDVRSVL 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	38/174 (22%)
timm50	NP_956959.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	61..93
timm50	NP_956959.1	NIF	183..330	CDD:281081	39/176 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810