DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8584 and Fcp1

DIOPT Version :9

Sequence 1:	NP_610404.1	Gene:	CG8584 / 35856	FlyBaseID:	FBgn0033322	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_001286846.1	Gene:	Fcp1 / 37925	FlyBaseID:	FBgn0035026	Length:	880	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	58/256 - (22%)
Similarity:	101/256 - (39%)	Gaps:	41/256 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PSGQFAV--------AVVSNLQRSRSSSDRRGLVLILLS------------SDLGTYIRR-LLAR 60
            |.|..|:        .||....|.......:|..::.||            :|.|..:|: ...:
  Fly   105 PGGDCAIQRYKSQRAGVVKKRLRKEGELLTKGDAILELSECIHTTVIKDMCADCGADLRQNENGQ 169

  Fly    61 VAEKACTILRTYLGLSYREVSVSQDMAH----RLAVVGRKTLVLDLDETLVHSCYLDPDTHDNVG 121
            .:|.:..::.|...|...: .::|.:.|    ||....:..|::|||:|::|:      |:|.|
  Fly   170 TSEASVPMVHTMPDLKVTQ-KLAQKLGHDDTRRLLADRKLVLLVDLDQTVIHT------TNDTV- 226

  Fly   122 CSQLPEHAQPDYVLNISIDGMEPIVFRVFKRPHVDEFLDFVSKWYDLVIYTASLEVYAAQVVDHL 186
                |::.:..|  :..:.|.....:....||...|||:.:|:.|:|.|.|.....||..:...|
  Fly   227 ----PDNIKGIY--HFQLYGPHSPWYHTRLRPGTAEFLERMSQLYELHICTFGARNYAHMIAQLL 285

  Fly   187 D-AGRGLITRRFYRQHCRASSPMVSKDLTLVTPDMSGVLIIDNSPYAYRDFPDNAIPIKTF 246
            | .|:....|...|..|..::........|.....|.|.|||:....: :...|.|.:|.:
  Fly   286 DPEGKFFSHRILSRDECFNATSKTDNLKALFPNGDSMVCIIDDREDVW-NMASNLIQVKPY 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8584	NP_610404.1	HIF-SF_euk	95..270	CDD:274055	39/153 (25%)
Fcp1	NP_001286846.1	Biotinyl_lipoyl_domains	59..142	CDD:299706	7/36 (19%)
		FCP1_euk	202..348	CDD:131304	40/158 (25%)
		COG5275	481..>658	CDD:227600
		BRCT	587..665	CDD:278934
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5190
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810