DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8738 and prss60.1

DIOPT Version :9

Sequence 1:	NP_610403.1	Gene:	CG8738 / 35855	FlyBaseID:	FBgn0033321	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	285	Identity:	89/285 - (31%)
Similarity:	136/285 - (47%)	Gaps:	43/285 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 LKGCGYSNPKGLYYQLDGYNN----GESVF-AEFPWMVAL-MDMEGNFVCGGTLIHPQLVLTSAH 243
            |..||          |...||    |.:.| ..:||.|:| ..:.|...|||:||:.:.|||:||
Zfish    22 LNVCG----------LAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEWVLTAAH 76

  Fly   244 NVFNRSEDSLLVRAGDWDLNSQTELHPYQM-RAISELHRHENFNNLTLYNDIALVVLERPFQVAP 307
            .:...:..||||..|.   .:|..::.|:: |.:|.:..|.::||||..|||||:.|......:.
Zfish    77 CLPRITTSSLLVFLGK---TTQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSAVTFSN 138

  Fly   308 HIQPICLPPPETPQMEAELRSASCLATGWG-LRYSTSRTMENLLKRIELPAVDHESCQRLLRHTV 371
            :|:|:||    ..|........|...|||| ::...:.....:|:...:|.|.::.|..||..
Zfish   139 YIRPVCL----AAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGS-- 197

  Fly   372 LGRRYNLHPSFTCAGGVK-GKDTCMGDGGSPLF---CTLPGQKDRYQLVGLVSWGIECAEKDVPA 432
             |...|   :..|||.:: |:|||.||.|.|:.   |.:..|.      |:.|||..||:...|.
Zfish   198 -GSVTN---NMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQS------GITSWGYGCADPYSPG 252

  Fly   433 AYTNVAYLRNWIDEQVTKS--GFPL 455
            .||.|:..::||:..:.::  ||.|
Zfish   253 VYTRVSQYQSWINSIIVQNLPGFVL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8738	NP_610403.1	Tryp_SPc	207..447	CDD:238113	79/247 (32%)
CG8738	NP_610403.1	Tryp_SPc	207..444	CDD:214473	77/244 (32%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	78/249 (31%)
		Tryp_SPc	34..267	CDD:238113	80/251 (32%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587388
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840