DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8738 and prss60.2

DIOPT Version :9

Sequence 1:	NP_610403.1	Gene:	CG8738 / 35855	FlyBaseID:	FBgn0033321	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	264	Identity:	82/264 - (31%)
Similarity:	129/264 - (48%)	Gaps:	33/264 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 GYNNGESVFAEFPWMVALMDME-GNFVCGGTLIHPQLVLTSAHNVFNRSEDSLLVRAGDWDLNSQ 265
            |.|..|   ..:||.|:|.... |...|||:||..:.|||:||.:...||.||:|..|   ..:|
Zfish    37 GVNAPE---GSWPWQVSLQSPRYGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLG---RRTQ 95

  Fly   266 TELHPYQ-MRAISELHRHENFNNLTLYNDIALVVLERPFQVAPHIQPICLPPPETPQMEAELRSA 329
            ..::.:: .|.::::..|.::|:.|..|||||:.|........:|:|:||    ..|........
Zfish    96 QGVNTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCL----AAQNSVYSAGT 156

  Fly   330 SCLATGWG-LRYSTSRTMENLLKRIELPAVDHESCQ-RLLRHTVLGRRYNLHPSFTCAGGVK-GK 391
            |...|||| ::...:.....:|:...:|.|.::.|. :|...||..       :..|||..| ||
Zfish   157 SSWITGWGDVQAGVNLPAPGILQETMIPVVANDRCNAQLGSGTVTN-------NMICAGLAKGGK 214

  Fly   392 DTCMGDGGSPL---FCTLPGQKDRYQLVGLVSWGIECAEKDVPAAYTNVAYLRNWIDEQVTKS-- 451
            |||.||.|.|:   .||:      :...|:.|||..||:.:.|..||.|:..::||..:::::
Zfish   215 DTCQGDSGGPMVTRLCTV------WIQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKISQNQP 273

  Fly   452 GFPL 455
            ||.|
Zfish   274 GFIL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8738	NP_610403.1	Tryp_SPc	207..447	CDD:238113	77/247 (31%)
CG8738	NP_610403.1	Tryp_SPc	207..444	CDD:214473	75/244 (31%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	77/249 (31%)
		Tryp_SPc	34..267	CDD:238113	79/252 (31%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840