Protein Alignment CG8738 and PRSS50

DIOPT Version :10

• Sequence 1: NP_610403.1
• Gene: CG8738 / 35855
• FlyBaseID: FBgn0033321
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_037402.1
• Gene: PRSS50 / 29122
• HGNCID: 17910
• Length: 385
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 97/398 - (24%)
• Similarity: 157/398 - (39%)
• Gaps: 116/398 - (29%)

  Fly    86 RRKNIWASSDNPLEGEPKPNLVGA-KEDEPGYKSCGVKRECVPRHLCSTGVVNEDGRYIIKPRI- 148
            |....|.:.:.|          || ...:|..:|.    :|||:..|.:.          :||:
Human    33 RSAGCWGAGEAP----------GALSTADPADQSV----QCVPKATCPSS----------RPRLL 73

  Fly   149 ------------NEESNFGCRVVEECCPLGDQIEEGR-NPIQRNVKDFLLKGCGYSNPKGLYYQL 200
                        ..|:.|             .:.||: :|         .:.||:|     |.|.
Human    74 WQTPTTQTLPSTTMETQF-------------PVSEGKVDP---------YRSCGFS-----YEQD 111

  Fly   201 DGYNNGESVFAEFPWMVALMDMEGNFVCGGTLIHPQLVLTSAHNVFNRSEDSLL-VRAGD-W-DL 262
            ....:.|:|...:||||::. ..|..:|.||:|..|.|||.||.:..|  |.:. ||.|. | |.
Human   112 PTLRDPEAVARRWPWMVSVR-ANGTHICAGTIIASQWVLTVAHCLIWR--DVIYSVRVGSPWIDQ 173

  Fly   263 NSQTELH-PYQMRAISELHRHENF-NNLTLYNDIALVVLERPFQVAPHIQPICLPPPETPQMEAE 325
            .:||... |.....:...:|.:.| :.:...|||.|:.|::..:.:.:::|||||..:....:
Human   174 MTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKD-- 236

  Fly   326 LRSASCLATGWGL-----RYSTSRTMENLLKRIELPAVDHESCQRLLRHTVLGRRYNLHPSFT-- 383
              .:.|..|||||     .:...||::..    |:..::::.|.            |.:.:||
Human   237 --HSRCTVTGWGLSKADGMWPQFRTIQEK----EVIILNNKECD------------NFYHNFTKI 283

  Fly   384 ------------CAGGVKGKDTCMGDGGSPLFCTLPGQKDRYQLVGLVSWGIECAEKDVPAAYTN 436
                        ||.....:..|....|.||.|::.|   .:.||||||||..|.:.:.|..|..
Human   284 PTLVQIIKSQMMCAEDTHREKFCYELTGEPLVCSMEG---TWYLVGLVSWGAGCQKSEAPPIYLQ 345

  Fly   437 VAYLRNWI 444
            |:..::||
Human   346 VSSYQHWI 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8738	NP_610403.1	CLIP_1	112..163	CDD:465709	10/63 (16%)
		Tryp_SPc	207..447	CDD:238113	74/262 (28%)
PRSS50	NP_037402.1	Tryp_SPc	118..353	CDD:238113	72/260 (28%)