DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8586 and prss60.2

DIOPT Version :9

Sequence 1:	NP_001286204.1	Gene:	CG8586 / 35854	FlyBaseID:	FBgn0033320	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	247	Identity:	80/247 - (32%)
Similarity:	120/247 - (48%)	Gaps:	30/247 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 GEFPWMVGIFTGRQ-EFLCGGTLIHPRLVVTTSHNLVNETVDTLVARAGDWDLNSLNEPYPHQGS 260
            |.:||.|.:.:.|. ...|||:||....|:|.:|.|...:..:||...|......:|   .|:.|
Zfish    43 GSWPWQVSLQSPRYGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLGRRTQQGVN---THETS 104

  Fly   261 R-IKEIIMHSEFDPNSLYNDIALLLLDEPIRLAPHIQPLCLPPPESPELTNQLLS--VTCYATGW 322
            | :.:||:||.::.|:..||||||.|...:....:|:|:||      ...|.:.|  .:.:.|||
Zfish   105 RNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCL------AAQNSVYSAGTSSWITGW 163

  Fly   323 GTKEAGSD-KLEHVLKRINLPLVEREECQAKLRNTRLEARFRLRPSFICAG-GDPGKDTCKGDGG 385
            |..:||.: ....:|:...:|:|..:.|.|:|.:.      .:..:.|||| ...|||||:||.|
Zfish   164 GDVQAGVNLPAPGILQETMIPVVANDRCNAQLGSG------TVTNNMICAGLAKGGKDTCQGDSG 222

  Fly   386 SPL---FCQMPGEMDRYQLVGIVSWGVECAVEDIPAVYVNVPHLRGWIDEKI 434
            .|:   .|.:      :...||.|||..||..:.|.||..|...:.||..||
Zfish   223 GPMVTRLCTV------WIQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8586	NP_001286204.1	Tryp_SPc	197..433	CDD:238113	78/244 (32%)
CG8586	NP_001286204.1	Tryp_SPc	197..430	CDD:214473	76/241 (32%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	76/241 (32%)
		Tryp_SPc	34..267	CDD:238113	78/244 (32%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587381
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840