DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8586 and Prss44

DIOPT Version :9

Sequence 1:	NP_001286204.1	Gene:	CG8586 / 35854	FlyBaseID:	FBgn0033320	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	XP_008764869.1	Gene:	Prss44 / 501060	RGDID:	1560940	Length:	373	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	100/396 - (25%)
Similarity:	167/396 - (42%)	Gaps:	102/396 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 WL------VERTTTVPSTIRNKVSSVLEPPPNESCGQNMECVPRKLCRDNIINDSGISLINPRIS 135
            ||      :.:...||.|:.:     |.|.|:|                |.::|.|   :||:..
  Rat    14 WLLLLQTRLGKAPMVPGTLPS-----LSPLPSE----------------NGLDDPG---VNPQER 54

  Fly   136 PI----QCSKSLYRCCAVDQKVDDSESPYLVKQANFKYKNCGYSNPKGLIP---------DNDKF 187
            |:    :.|..|        |...|.:|:               :..|..|         ....|
  Rat    55 PLTGMPETSLPL--------KPGGSMTPF---------------DSMGFTPGHSFSSMSLSRQSF 96

  Fly   188 -PYSEDVSIFG---------------EFPWMVGIFTGRQEFLCGGTLIHPRLVVTTSHNLVNETV 236
             |:....|..|               ::||.|.:...:|. :|||:||....|:|.:| .|...:
  Rat    97 PPWIPPTSACGHRTARIVGGKPAPIRKWPWQVSLQVHKQH-ICGGSLISKWWVMTAAH-CVYGHL 159

  Fly   237 DTLVARAGDWDL-NSLNEPYPHQGSRIKEIIMHSEFD-PNSLYNDIALLLLDEPIRLAPHIQPLC 299
            |.:|: .|:.|| :|::...|     :::||:|.::. ..::.:||||:||..|:..:.:|||:|
  Rat   160 DYVVS-MGEADLWSSMSVKIP-----VQDIIVHQDYSVMRTIVHDIALVLLAFPVNYSVNIQPVC 218

  Fly   300 LPPPESPELTNQLLSVTCYATGWG-TKEAGSDKLEHVLKRINLPLVEREECQAKLRNTRLEARFR 363
            :  ||...|...  ...|:.|||| |.|.|  :...||:.::|.::..|.|...|::........
  Rat   219 I--PEKSFLVQP--GTLCWVTGWGKTIERG--RSSRVLREVDLSIIRHERCNQILKDITGRIFTL 277

  Fly   364 LRPSFICAGGDPGKDTCKGDGGSPLFCQMPGEMDRYQLVGIVSWGVECAVEDIPAVYVNVPHLRG 428
            ::...:|.....|.|.|:||.|.|:.|:.   ...:..|||||||:.|.....|.:|..|.:.|.
  Rat   278 VQEGGVCGYNKKGGDACQGDSGGPMVCEF---NKTWVQVGIVSWGLGCGRIGYPGIYTEVSYYRD 339

  Fly   429 WIDEKI 434
            ||.:::
  Rat   340 WIIKEL 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8586	NP_001286204.1	Tryp_SPc	197..433	CDD:238113	75/253 (30%)
CG8586	NP_001286204.1	Tryp_SPc	197..430	CDD:214473	73/250 (29%)
Prss44	XP_008764869.1	Tryp_SPc	112..341	CDD:214473	72/245 (29%)
Prss44	XP_008764869.1	Tryp_SPc	113..341	CDD:238113	72/244 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	162	1.000	Domainoid score	I3893
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910