DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon44E and ela2

DIOPT Version :9

Sequence 1:	NP_001286203.1	Gene:	Jon44E / 35853	FlyBaseID:	FBgn0001285	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001132936.1	Gene:	ela2 / 403061	ZFINID:	ZDB-GENE-041117-1	Length:	266	Species:	Danio rerio

Alignment Length:	281	Identity:	88/281 - (31%)
Similarity:	131/281 - (46%)	Gaps:	40/281 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFVFLACLAVASAGVVPSESARAVPVKDMPRAGKIEGRITNGYPAYEGKIPYIVGLSFNDGG- 64
            ||| |.||.....:.|.            ..|....|:.|:..|........|:...|.:..|.
Zfish     1 MKL-VILALFIAGAYGC------------GQPTYKPIDSRVVGGSDVRPNSWPWQASLQYQSGSS 52

  Fly    65 --YWCGGSIIDHTWVLTAAHCTNSANH-VLIYFGASFRHEAQY-----THWVSRSDMIQHPDWND 121
              :.|||::||..||||||||.:|..: ||:     .:|....     :..:|.:.:|.|.:|:.
Zfish    53 FYHTCGGTLIDKQWVLTAAHCISSRTYRVLL-----GKHNLPLSSESGSQAISPARIIVHENWDS 112

  Fly   122 F-LNNDIALIRI-PHVDFWSLVNKVELPSYND--RYNSYSGWWAVASGWGLTDNNSGMSNYLNCV 182
            : :.||||||:: ..|.|...::...||....  .:||.    ...:|||.......:::.|...
Zfish   113 YNIRNDIALIKLSTPVTFTDKISPACLPDSGSILPHNSP----CYVTGWGRLWTGGPIADILQQA 173

  Fly   183 DVQIIDNNDC-RNYYGSNYITDNTICINTDGGKSSCSGDSGGPLVLHDNN---RIVGIVSFGSGE 243
            .:.|:|...| ::.:..|.:||..:|...||..|||:|||||||.....:   .:.|||||||..
Zfish   174 LLPIVDQATCTKSDWWGNLVTDLMVCAGGDGVVSSCNGDSGGPLNCQRRDGTWDVHGIVSFGSSL 238

  Fly   244 GCT-AGRPAGFTRVTGYLDWI 263
            ||. ..:|:.||||:||:.||
Zfish   239 GCNYPKKPSVFTRVSGYIPWI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_001286203.1	Tryp_SPc	40..263	CDD:214473	77/240 (32%)
Jon44E	NP_001286203.1	Tryp_SPc	41..266	CDD:238113	78/241 (32%)
ela2	NP_001132936.1	Tryp_SPc	27..259	CDD:214473	77/240 (32%)
ela2	NP_001132936.1	Tryp_SPc	28..262	CDD:238113	78/241 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	1	0.900	-	-		E33208_3BBU3
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4253
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.860