DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon44E and Jon66Cii

DIOPT Version :9

Sequence 1:	NP_001286203.1	Gene:	Jon44E / 35853	FlyBaseID:	FBgn0001285	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	161/276 - (58%)
Similarity:	194/276 - (70%)	Gaps:	20/276 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFVFLACLAVASA--GVVP---SESARAVPVKDMPRAGKIEGRITNGYPAYEGKIPYIVGLSF 60
            ||.|:.:..||||||  ..:|   :|....|..|||      :|||||||||.|||.||.|||.|
  Fly     1 MKAFIAILALAVASASGATMPRLATEKLTPVHTKDM------QGRITNGYPAEEGKAPYTVGLGF 59

  Fly    61 NDGGYWCGGSIIDHTWVLTAAHCTNSANHVLIYFGASFRHEAQYTHWVSRSDMIQHPDWNDFLNN 125
            : ||:|||||||.|.|||||.||...|:.|.:||||::|..||:||||...:.|:|.      :.
  Fly    60 S-GGWWCGGSIIAHDWVLTAEHCIGDADSVTVYFGATWRTNAQFTHWVGNGNFIKHS------SA 117

  Fly   126 DIALIRIPHVDFWSLVNKVELPSYNDRYNSYSGWWAVASGWGLTDNNSGMSNYLNCVDVQIIDNN 190
            |||||||||||||.:||||||||||||||.|:.|||||.|||.|.:.|.:.:||.|||:|||.|:
  Fly   118 DIALIRIPHVDFWHMVNKVELPSYNDRYNDYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNS 182

  Fly   191 DCRNYYGSNYITDNTICINTDGGKSSCSGDSGGPLVLHDNNRIVGIVSFGSGEGCTAGRPAGFTR 255
            :|..||||  :.||.:|:.|..|||:|.||||||||.||..::||:.:|||..||.:|.||||.|
  Fly   183 ECSGYYGS--VGDNILCVRTPDGKSTCGGDSGGPLVTHDGTKLVGVTNFGSVAGCQSGAPAGFQR 245

  Fly   256 VTGYLDWIRDHTGIVY 271
            ||.:||||||||||.|
  Fly   246 VTYHLDWIRDHTGIAY 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_001286203.1	Tryp_SPc	40..263	CDD:214473	136/222 (61%)
Jon44E	NP_001286203.1	Tryp_SPc	41..266	CDD:238113	138/224 (62%)
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	136/222 (61%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	138/224 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470783
Domainoid	1	1.000	70	1.000	Domainoid score	I6224
eggNOG	1	0.900	-	-		E33208_3BBU3
Homologene	1	1.000	-	-		H134616
Inparanoid	1	1.050	192	1.000	Inparanoid score	I6301
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101263at6656
OrthoFinder	1	1.000	-	-		FOG0000557
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	11	10.900