Protein Alignment Jon44E and KLK2

DIOPT Version :10

• Sequence 1: NP_724699.1
• Gene: Jon44E / 35853
• FlyBaseID: FBgn0001285
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 77/291 - (26%)
• Similarity: 117/291 - (40%)
• Gaps: 70/291 - (24%)

  Fly     5 VFLACLAVASAGVVPSESARAVPVKDMPRAGKIEGRITNGYPAYEGKIPYIVGLSFNDGGYWCGG 69
            |....|:|...|.||                .|:.||..|:...:...|:.|.: ::.|...|||
Human     5 VLSIALSVGCTGAVP----------------LIQSRIVGGWECEKHSQPWQVAV-YSHGWAHCGG 52

  Fly    70 SIIDHTWVLTAAHCTNSANHVLIYFGASFRHEAQYTHWVSRSDMIQ---------------HPDW 119
            .::...||||||||....:.|                |:.|.::.:               ||.:
Human    53 VLVHPQWVLTAAHCLKKNSQV----------------WLGRHNLFEPEDTGQRVPVSHSFPHPLY 101

  Fly   120 NDFL------------NNDIALIRIPH-VDFWSLVNKVELPSYNDRYNSYSGWWAVASGWGLTDN 171
            |..|            ::|:.|:|:.. .....:|..:.||:.....    |....|||||..:.
Human   102 NMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPAL----GTTCYASGWGSIEP 162

  Fly   172 NSGM-SNYLNCVDVQIIDNNDCRNYYGSNYITDNTICINT-DGGKSSCSGDSGGPLVLHDNNRIV 234
            ...: ...|.||.:.::.|:.|...| |..:|:..:|... .|||.:|.||||||||.  |..:.
Human   163 EEFLRPRSLQCVSLHLLSNDMCARAY-SEKVTEFMLCAGLWTGGKDTCGGDSGGPLVC--NGVLQ 224

  Fly   235 GIVSFGSGEGCTAGRPAGFTRVTGYLDWIRD 265
            ||.|:|........:||.:|:|..|..||:|
Human   225 GITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_724699.1	Tryp_SPc	41..266	CDD:238113	69/255 (27%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	69/255 (27%)