DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon44E and C1s2

DIOPT Version :9

Sequence 1:	NP_001286203.1	Gene:	Jon44E / 35853	FlyBaseID:	FBgn0001285	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_776289.2	Gene:	C1s2 / 317677	MGIID:	3644269	Length:	694	Species:	Mus musculus

Alignment Length:	274	Identity:	84/274 - (30%)
Similarity:	116/274 - (42%)	Gaps:	46/274 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ESARAVPVKDMP-RAGKIEGRITNGYPAYEGKIPYIVGLSFNDGGYWCGGSIIDHTWVLTAAHCT 84
            |..|.:||..:| ...:::.:|..|.||.....|:.|  .||..  ..||::|:..|||||||..
Mouse   423 ELPRCIPVCGVPTEPFQVQQKIFGGQPAKIENFPWQV--FFNHP--TAGGALINEYWVLTAAHVV 483

  Fly    85 NSANHVLIYFGASFRHEAQ-------YTHWVSRSDMIQHPDW--NDFLN------NDIALIRIPH 134
            ...:...:|.|.:....|.       ||..|     |.||.|  :|.||      |||||:::..
Mouse   484 EKNSDPSMYAGITALRLADLENAQRLYTKRV-----IIHPGWKEDDDLNPRTNFDNDIALVQLKD 543

  Fly   135 -VDFWSLVNKVELPSYNDRYNSYSGWWAVASGWGLTDNNSGMSNYLNCVDVQIIDNNDCRNYYGS 198
             |......:.:.||..:..||...|...:.||||.|:....:.| |....|.:.....|:.....
Mouse   544 PVKMGPKFSPICLPGTSSEYNLSPGDMGLISGWGRTEKRLHVIN-LRGAKVPVTSLETCKQVKEE 607

  Fly   199 N--------YITDNTICINTDGGKSSCSGDSGG------PLVLHDNNRIVGIVSFGSGEGCTAGR 249
            |        .||||.||.. :.|..||.|||||      |.|......:.|:||:|.    ..|.
Mouse   608 NPTARPEDYVITDNMICAG-EKGVDSCKGDSGGAFAFQVPNVKAPKFYVAGLVSWGK----KCGA 667

  Fly   250 PAGFTRVTGYLDWI 263
            ...:|:|..|:|||
Mouse   668 YGVYTKVKNYVDWI 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_001286203.1	Tryp_SPc	40..263	CDD:214473	77/252 (31%)
Jon44E	NP_001286203.1	Tryp_SPc	41..266	CDD:238113	79/253 (31%)
C1s2	NP_776289.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:291342
		CUB	181..293	CDD:278839
		CCP	300..361	CDD:153056
		CCP	365..428	CDD:153056	2/4 (50%)
		Tryp_SPc	443..681	CDD:214473	77/252 (31%)
		Tryp_SPc	444..684	CDD:238113	79/253 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000