DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon44E and Cela3b

DIOPT Version :9

Sequence 1:	NP_001286203.1	Gene:	Jon44E / 35853	FlyBaseID:	FBgn0001285	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001100162.1	Gene:	Cela3b / 298567	RGDID:	1307819	Length:	269	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	79/283 - (27%)
Similarity:	123/283 - (43%)	Gaps:	38/283 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFVFLACLAVASAGVVPSESARAVPVKDMPRAGKIEGRITNGYPAYEGKIPYIVGLSFNDGG- 64
            ::|...|..:|:||....||.:.              ..|:.||..|.....|:.|.|.:...|
  Rat     2 LRLLCSLLLVALASGCGQPSYNP--------------SSRVVNGEDAVPYSWPWQVSLQYEKDGS 52

  Fly    65 --YWCGGSIIDHTWVLTAAHCTNSANH---VLIYFGASFRHEAQYTHWVSRSDMIQHPDWND--- 121
              :.|||::|...||:||.||.:::..   ||..|........:....|:..|:..||.||.
  Rat    53 FHHTCGGTLIAPDWVMTAGHCISTSRTYQVVLGEFERGVEEGPEQVIPVNAGDLFVHPKWNSNCV 117

  Fly   122 FLNNDIALIRIPH-VDFWSLVNKVELPSYNDRYNSYSGWWAVASGWGLTDNNSGMSNYLNCVDVQ 185
            ...|||||:::.. ......|....||...:...  :|.....||||....|..:.:.|....:.
  Rat   118 SCGNDIALVKLSRSAQLGDTVQLACLPPAGEILP--NGAPCYISGWGRLSTNGPLPDKLQQALLP 180

  Fly   186 IIDNNDCR--NYYGSNYITDNTICINTDGG--KSSCSGDSGGPLVLHDNN---RIVGIVSFGSGE 243
            ::|...|.  :::|.: :....:|.   ||  :|.|:|||||||.....|   ::.|:.||.|..
  Rat   181 VVDYAHCSKWDWWGFS-VKKTMVCA---GGDIQSGCNGDSGGPLNCPAENGTWQVHGVTSFVSSL 241

  Fly   244 GC-TAGRPAGFTRVTGYLDWIRD 265
            || |..:|..||||:.:.:||.:
  Rat   242 GCNTLKKPTVFTRVSAFNEWIEE 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_001286203.1	Tryp_SPc	40..263	CDD:214473	70/240 (29%)
Jon44E	NP_001286203.1	Tryp_SPc	41..266	CDD:238113	71/243 (29%)
Cela3b	NP_001100162.1	Tryp_SPc	27..262	CDD:214473	70/240 (29%)
Cela3b	NP_001100162.1	Tryp_SPc	28..265	CDD:238113	71/243 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I4367
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960