Protein Alignment Jon44E and KLK13

DIOPT Version :10

• Sequence 1: NP_724699.1
• Gene: Jon44E / 35853
• FlyBaseID: FBgn0001285
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 94/280 - (33%)
• Similarity: 131/280 - (46%)
• Gaps: 40/280 - (14%)

  Fly     3 LFVFLACLAVASAGVVPSESARAVPVKDMPRAGKIEGRITNGYPAYEGKIPYIVGLSFNDGGYWC 67
            |.:.:|.|.:|.:|.|..||::.:      ......|.:..||..:....|:...| ...|...|
Human     4 LALVIASLTLALSGGVSQESSKVL------NTNGTSGFLPGGYTCFPHSQPWQAAL-LVQGRLLC 61

  Fly    68 GGSIIDHTWVLTAAHCTNSANHVLIYFG--ASFRHEA-----QYTHWVSRSDMIQHPDWN---DF 122
            ||.::...||||||||....  :.:|.|  |..|.||     :..|      .|.||::.   ..
Human    62 GGVLVHPKWVLTAAHCLKEG--LKVYLGKHALGRVEAGEQVREVVH------SIPHPEYRRSPTH 118

  Fly   123 LN--NDIALIRIPH-VDFWSLVNKVELPSYNDRYNSYSGWWAVASGWGLTDNNSGMSNY---LNC 181
            ||  :||.|:.:.. |.....:..:.| |:|:|..  .|.....||||.|  .|...||   |.|
Human   119 LNHDHDIMLLELQSPVQLTGYIQTLPL-SHNNRLT--PGTTCRVSGWGTT--TSPQVNYPKTLQC 178

  Fly   182 VDVQIIDNNDCRNYYGSNYITDNTICINT-DGGKSSCSGDSGGPLVLHDNNRIVGIVSFGSGEGC 245
            .::|:..:.:||..|... ||||.:|..| :|||.||.||||||||.  |..:.||||:|.....
Human   179 ANIQLRSDEECRQVYPGK-ITDNMLCAGTKEGGKDSCEGDSGGPLVC--NRTLYGIVSWGDFPCG 240

  Fly   246 TAGRPAGFTRVTGYLDWIRD 265
            ...||..:|||:.|:.|||:
Human   241 QPDRPGVYTRVSRYVLWIRE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_724699.1	Tryp_SPc	41..266	CDD:238113	85/242 (35%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	85/240 (35%)