DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon44E and svh-1

DIOPT Version :9

Sequence 1:	NP_001286203.1	Gene:	Jon44E / 35853	FlyBaseID:	FBgn0001285	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	77/282 - (27%)
Similarity:	118/282 - (41%)	Gaps:	43/282 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LACLAVASAGVVPSESARAVPVKDMPRAGKIEGRITNGYPAYEGKIPYIVGLSFNDG--GYWCGG 69
            ::|::............|.|.|.....|.....|:..|:....|..|:...|. |..  .:.||.
Worm   679 ISCISQNGMSSASQCGLRYVEVNARDAAKSRIARVVGGFETVPGAFPWTAALR-NKATKAHHCGA 742

  Fly    70 SIIDHTWVLTAAHCTNSANHVLIYFGASFRHEAQYTHWVSRSD-------MIQ----HPDWNDFL 123
            ||:|.|.::|||||......|..|       |.....|.:...       .:|    :|.:.|..
Worm   743 SILDKTHLITAAHCFEEDERVSSY-------EVVVGDWDNNQTDGNEQIFYLQRIHFYPLYKDIF 800

  Fly   124 NNDIALIRIPH--VDFWSLVNKVELPSYNDRYNSYSGWWAVASGWGLTDNNSGM--SNYLNCVDV 184
            ::|||::.||:  ::|......:.|||.:..|.  .|...|.||||    :.|:  :..|....:
Worm   801 SHDIAILEIPYPGIEFNEYAQPICLPSKDFVYT--PGRQCVVSGWG----SMGLRYAERLQAALI 859

  Fly   185 QIIDNNDCRN---YYGSNYITDNTICIN-TDGGKSSCSGDSGGPLVLHDNNR---IVGIVSFGSG 242
            .||:..||.|   .|.|  ::.:..|.. .:||..||.||||||......:.   :.|::|:  |
Worm   860 PIINRFDCVNSSQIYSS--MSRSAFCAGYLEGGIDSCQGDSGGPFACRREDGAFVLAGVISW--G 920

  Fly   243 EGCTAGRPAG-FTRVTGYLDWI 263
            :||...:..| :|.|..||.||
Worm   921 DGCAQKKQPGIYTMVAPYLSWI 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_001286203.1	Tryp_SPc	40..263	CDD:214473	70/247 (28%)
Jon44E	NP_001286203.1	Tryp_SPc	41..266	CDD:238113	71/248 (29%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996	0/1 (0%)
		Tryp_SPc	713..945	CDD:238113	71/248 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910