DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon44E and F9

DIOPT Version :9

Sequence 1:	NP_001286203.1	Gene:	Jon44E / 35853	FlyBaseID:	FBgn0001285	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_032005.1	Gene:	F9 / 14071	MGIID:	88384	Length:	471	Species:	Mus musculus

Alignment Length:	246	Identity:	73/246 - (29%)
Similarity:	123/246 - (50%)	Gaps:	31/246 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RITNGYPAYEGKIPYIVGLSFNDGGYWCGGSIIDHTWVLTAAHCTNSANHVLIYFG---ASFRHE 101
            |:..|..|..|:||:.|.|: .:...:|||:||:..|::|||||....:.:.:..|   ...:.:
Mouse   236 RVVGGENAKPGQIPWQVILN-GEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEYNIDKKED 299

  Fly   102 AQYTHWVSRSDMIQHPDWNDFLN---NDIALIRIPHVDFWSLVNKVELP------SYNDRYNSY- 156
            .:....|.|:  |.|..:|..:|   :||||:.:   |...::|....|      .|.:.:..:
Mouse   300 TEQRRNVIRT--IPHHQYNATINKYSHDIALLEL---DKPLILNSYVTPICVANREYTNIFLKFG 359

  Fly   157 SGWWAVASGWGLTDNNSGMSNYLNCVDVQIIDNNDCRNYYGSNY-ITDNTICIN-TDGGKSSCSG 219
            ||:   .||||...|....::.|..:.|.::|...|..  .:.: |.:|..|.. .:|||.||.|
Mouse   360 SGY---VSGWGKVFNKGRQASILQYLRVPLVDRATCLR--STTFTIYNNMFCAGYREGGKDSCEG 419

  Fly   220 DSGGPLV--LHDNNRIVGIVSFGSGEGCT-AGRPAGFTRVTGYLDWIRDHT 267
            |||||.|  :...:.:.||:|:  ||.|. .|:...:|:|:.|::||::.|
Mouse   420 DSGGPHVTEVEGTSFLTGIISW--GEECAMKGKYGIYTKVSRYVNWIKEKT 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_001286203.1	Tryp_SPc	40..263	CDD:214473	70/240 (29%)
Jon44E	NP_001286203.1	Tryp_SPc	41..266	CDD:238113	71/242 (29%)
F9	NP_032005.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:291342
		Tryp_SPc	236..464	CDD:214473	70/240 (29%)
		Tryp_SPc	237..467	CDD:238113	71/242 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910