Protein Alignment Jon44E and CMA1

DIOPT Version :10

• Sequence 1: NP_724699.1
• Gene: Jon44E / 35853
• FlyBaseID: FBgn0001285
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001827.1
• Gene: CMA1 / 1215
• HGNCID: 2097
• Length: 247
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 78/270 - (28%)
• Similarity: 127/270 - (47%)
• Gaps: 42/270 - (15%)

  Fly     1 MKLFVFLACLAVASAGVVPSESARAVPVKDMPRAGKIEGRITNGYPAYEGKIPYIVGLSFNDGGY 65
            :.|.:||.|             :||       .||:|.|. |...|.....:.|:..::.|....
Human     6 LPLLLFLLC-------------SRA-------EAGEIIGG-TECKPHSRPYMAYLEIVTSNGPSK 49

  Fly    66 WCGGSIIDHTWVLTAAHCTNSANHVLIYFGASFRHEAQYTHWVSRSDMI---QHPDWN-DFLNND 126
            :|||.:|...:|||||||  :...:.:..||....|.:.| | .:.::|   :||.:| ..|::|
Human    50 FCGGFLIRRNFVLTAAHC--AGRSITVTLGAHNITEEEDT-W-QKLEVIKQFRHPKYNTSTLHHD 110

  Fly   127 IALIRIPHVDFWSL-VNKVELPSYNDRYNSY-SGWWAVASGWGLTDNNSGMSNYLNCVDVQIIDN 189
            |.|:::......:| |..:..||   ::|.. .|.....:|||.|......|:.|..|.::::|.
Human   111 IMLLKLKEKASLTLAVGTLPFPS---QFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDP 172

  Fly   190 NDCRNYYGSNYITDNTICI-NTDGGKSSCSGDSGGPLVLHDNNRIVGIVSFGSGEGCTAGRPAGF 253
            ..|.::  .::..:..:|: |....||:..|||||||:.....:  ||||:|..:   |..||.|
Human   173 QACSHF--RDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQ--GIVSYGRSD---AKPPAVF 230

  Fly   254 TRVTGYLDWI 263
            ||::.|..||
Human   231 TRISHYRPWI 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon44E	NP_724699.1	Tryp_SPc	41..266	CDD:238113	68/230 (30%)
CMA1	NP_001827.1	Tryp_SPc	22..243	CDD:238113	70/234 (30%)