Protein Alignment ptc and si:ch211-250m6.7

DIOPT Version :9

• Sequence 1: NP_523661.2
• Gene: ptc / 35851
• FlyBaseID: FBgn0003892
• Length: 1286
• Species: Drosophila melanogaster
• Sequence 2: XP_021327233.1
• Gene: si:ch211-250m6.7 / 565624
• ZFINID: ZDB-GENE-041210-239
• Length: 868
• Species: Danio rerio
• Alignment Length: 834
• Identity: 170/834 - (20%)
• Similarity: 308/834 - (36%)
• Gaps: 242/834 - (29%)

  Fly   329 VGGAK-RNRSGHLRKAQALQSVVQLMTEKEMYDQWQDNYKVHHLGWTQEKAAEVLNAWQRNFSRE 392
            :||.: :..|..|:.|:|:: :...:.||:                 .:..|:.|..:.:.||..
Zfish   180 IGGVETQPNSSMLKSAKAIR-LYYFLDEKK-----------------SKGNADWLEGFIQFFSNY 226

  Fly   393 VEQLLRKQSRIATNYDIYVFSSAA--------LDDILAKFSHPSALSIVIGVAVTVLYAFCTLLR 449
            .:     |.:::.:|    |:|.:        .|.::..|      ||...:|:.:....|..|
Zfish   227 TD-----QEKVSVSY----FTSVSRQNEFEGNTDSVIPLF------SITYALAINIAVLSCLRL- 275

  Fly   450 WRDPVRGQSSVGVAGVLLMCFSTAAGLGLSALLGIVFNAASTQVVPFLALGLGVDHIFMLTAAYA 514
              |.||.:..|.:.||:....:..|..||....|:.| |.:....|||.||:|||.:|::.:::.
Zfish   276 --DCVRTKVWVALLGVVSAGMAVLASFGLLLFCGMPF-AMTVGSAPFLILGVGVDDMFIMISSWQ 337

  Fly   515 ESNRREQTKLIL----KKVGPSILFSACSTAGSFFAAAFIPVPALKVFCLQAAIVMCSNLAAALL 575
            ::...:..:..|    |:.|.||..:..:...:|:.....|..:::.||:..:..:.......:.
Zfish   338 KTAVDKGVEFRLAEAYKEAGVSITITTLTDVLAFYIGLLTPFRSVQSFCMYTSTALLFCYLFNIT 402

  Fly   576 VFPAMISLDLRRRTAGRADIFCCCFPVWKEQPKVAPPVLPLNNNNGRGARHPKSC--------NN 632
            .|.|.::|:.||..:.|.  |..|..|    ||.:...:              ||        |.
Zfish   403 FFGACLALNGRREKSNRH--FLTCMTV----PKPSGDAV--------------SCCAGGAFDENT 447

  Fly   633 NRVPLPAQNPLLEQRADIPGSSHSLASFSLATFAFQHYTPFLMRSWVKFLTVMGFLAALISSLYA 697
            |:                   .|.:   .:..|..::|.|||.:.|||.|..:.:...|..|:|.
Zfish   448 NK-------------------EHEM---PMEVFFKKYYGPFLAKVWVKVLVCLIYAGYLAVSIYG 490

  Fly   698 STRLQDGLDIIDLVPKDSNEHKFLDAQTRLFGFYSMYAVTQGNFEYPTQQQLLRDYHDSFVRVPH 762
            ..::::|||:..|....|....:.|.:...|..:.           |....:::|.|
Zfish   491 CFQMEEGLDLKHLATDGSYVADYYDREDEFFSAFG-----------PNVMLVIKDEH-------- 536

  Fly   763 VIKNDNGGLPDFWLLLFSEWLGNLQKIFD---EEYRDGRLTKECWFPNASSDAILAYKLIVQTGH 824
                            |..|..:.:|..|   :.:||  ||.
Zfish   537 ----------------FQYWSPDARKSLDLCLKNFRD--LTM----------------------- 560

  Fly   825 VDNPVDKELVLTNRL-------VNSDGIINQRAFYNYLSAWATNDVFAYGASQGKLYPEPRQYFH 882
                ||.|:.||:.|       .:|..:.|:..|...|.|:.....|::..           :|.
Zfish   561 ----VDSEIPLTSWLDAYMKFGQSSFDLNNEMIFKTQLPAFLNRSEFSHDV-----------HFT 610

  Fly   883 QPNEYDLKIPKSLPLVYAQMPFYLHGLTDTSQIKTLI----------------GHIR---DLSVK 928
            ..|            :.|...|     ..|..|||.|                |.:.   ||.|.
Zfish   611 DNN------------INATRMF-----IQTVNIKTAIDEKDMLNAFREAAHTCGRLETPVDLIVY 658

  Fly   929 YEGFGLPNYPSGIPFIFWEQYMTLRSSLAMIL---ACVLLA-ALVLVSLLLLSVWAAVLVILSVL 989
            :..           ||:::||..:.|:....|   .||:|. :|:|:...|.|:| ....|.||:
Zfish   659 HPA-----------FIYFDQYAVIVSNTIQNLVAATCVMLVISLLLIPHPLCSLW-VTFSIASVI 711

  Fly   990 ASLAQIFGAMTLLGIKLSAIPAVILILSVGMMLCFNVLISLGFMTSVGNRQRRVQLSMQMSLG-P 1053
            ..||   |.|.|..|.|.::..:.|::.:|..:.|:..||..|::|..:............|| |
Zfish   712 VGLA---GFMALWDISLDSVSMINLVICIGFSVDFSAHISYAFVSSEKSSANEKATDALHKLGYP 773

  Fly  1054 LVHGMLTSGVAVFMLSTSPFEFVIRHFCWLLLVVLCVGACNSLLVFPILLSMVG 1107
            ::.|.:::...|.:|:.:. .::.|.|..::.:|:..||.:.::..|:.||.:|
Zfish   774 IIQGAVSTIAGVVVLAAAK-SYIFRTFFKIMFLVILFGALHGIVFLPVFLSFLG 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ptc	NP_523661.2	2A060602	17..1134	CDD:273338	170/834 (20%)
		MMPL	454..598	CDD:304422	36/147 (24%)
si:ch211-250m6.7	XP_021327233.1	Patched	54..823	CDD:330476	167/829 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910