Protein Alignment CG8635 and Zc3h15

DIOPT Version :10

• Sequence 1: NP_610401.1
• Gene: CG8635 / 35850
• FlyBaseID: FBgn0033317
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001010963.1
• Gene: Zc3h15 / 362154
• RGDID: 1359234
• Length: 426
• Species: Rattus norvegicus
• Alignment Length: 431
• Identity: 226/431 - (52%)
• Similarity: 289/431 - (67%)
• Gaps: 36/431 - (8%)

  Fly     1 MPPKK-APPGPSKKTEQKKKEKVIEDKTFGLKNKKGNKQQKFIQQVQKQVQSGGQHPRQ----DG 60
            ||||| |..|.|||.|||||||:|||||||||||||.||||||:.|..||:.|.|:|||    :.
  Rat     1 MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEA 65

  Fly    61 DK--RKEEKEKKLAEQREMALIFKP-VQTQKVEKGTDPKSVVCAFFKQGTCTKGDKCKFSHDLSQ 122
            :|  :|::|:|:|.|..|   :||| |..||:.||.|||||||||||||.|||||||||||||:.
  Rat    66 EKKLKKDDKKKELQELNE---LFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTL 127

  Fly   123 ENKVEKRSIYVDMRDED---DPMTNWDDAKLKEVVEKK-SSGEKQRPTTDIICKFFLEAVEKSKY 183
            |.|.||||:|:|.|||:   |.|.|||:.||:|||.|| ...||::|.|.|:|:.||||:|.:||
  Rat   128 ERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCRHFLEAIENNKY 192

  Fly   184 GWFWECPNGG-KCIYRHALPAGYVLKRDKKKEEKPTEISLVDLIEKERAALGPNQTRVTLESFLA 247
            ||||.||.|| .|:||||||.|:|||:|||||||..||||.||||:||:|||||.|::|||||||
  Rat   193 GWFWVCPGGGDNCMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLA 257

  Fly   248 WKKRKIAEKKAKLAAEEERKKSDFSKGKQFGISGREMFSFNPDLVDDGPMEEGDAAFDVYNREDD 312
            |||||..||..||..:.||:|:||..||...|||||:|.|.|:||:|...|..|..:......|:
  Rat   258 WKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYIQGTGGDE 322

  Fly   313 DDNAVEFKELDLAALSLAAKEVDGSG-TIAS------------TNRLLDQATEAAKTAAAEDAAA 364
            .|::|...::||:.  ...::|:.:| |:||            .|:|.:.:...|:.....|...
  Rat   323 VDDSVGVNDIDLSL--YVPRDVEETGITVASLERFSTYASDKDENKLSEASGGLAENGERSDLDE 385

  Fly   365 DEDGPSSSAPANDAAPINKDLFV-----DLAGELDDLDLDD 400
            |..|......:.||.|::::||.     :|..||:.|||::
  Rat   386 DSGGGGQENGSIDAVPVDENLFTGEDLDELEEELNTLDLEE 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8635	NP_610401.1	COG5252	1..314	CDD:227577	200/325 (62%)
Zc3h15	NP_001010963.1	COG5252	1..325	CDD:227577	200/326 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		22/28 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	53..74		7/20 (35%)
		Required for interaction with DRG1. /evidence=ECO:0000250	236..260		18/23 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	302..326		6/23 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	359..426		17/66 (26%)