Protein Alignment CG8635 and zc3h15

DIOPT Version :10

• Sequence 1: NP_610401.1
• Gene: CG8635 / 35850
• FlyBaseID: FBgn0033317
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_956182.1
• Gene: zc3h15 / 334307
• ZFINID: ZDB-GENE-030131-6239
• Length: 433
• Species: Danio rerio
• Alignment Length: 441
• Identity: 228/441 - (51%)
• Similarity: 288/441 - (65%)
• Gaps: 49/441 - (11%)

  Fly     1 MPPKK-APPGPSKKTEQKKKEKVIEDKTFGLKNKKGNKQQKFIQQVQKQVQSGGQHPRQ------ 58
            ||||| ||...:|||::|||||:|||||||||||||.||||||:.|.:||:.|.|:.||
Zfish     1 MPPKKPAPAAANKKTQEKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTQQVKFGQQNARQIAAAES 65

  Fly    59 DGDKRKEEKEKKLAEQREMALIFKP-VQTQKVEKGTDPKSVVCAFFKQGTCTKGDKCKFSHDLSQ 122
            :..|:|::|:|:|:|..|   :||| |..|||.||.|||||:|||||||.||||||||||||||.
Zfish    66 EKTKKKDDKKKELSELNE---LFKPVVAAQKVSKGVDPKSVLCAFFKQGQCTKGDKCKFSHDLSL 127

  Fly   123 ENKVEKRSIYVDMRD----EDDPMTNWDDAKLKEVVEKK-SSGEKQRPTTDIICKFFLEAVEKSK 182
            |.|.||||:|||.||    |.|.|.|||:.||:|||.|| ...||::..|.|:||:||:|:|.:|
Zfish   128 ERKCEKRSLYVDGRDDELLEKDTMENWDEKKLEEVVNKKHGEAEKKKAKTQIVCKYFLDAIENNK 192

  Fly   183 YGWFWECPNGG-KCIYRHALPAGYVLKRDKKKEEK-PTEISLVDLIEKERAALGPNQTRVTLESF 245
            |||||.||.|| .|:||||||.|:|||:|||.||| ..||||.||||.||:.||.|.||:|||:|
Zfish   193 YGWFWVCPGGGDNCMYRHALPVGFVLKKDKKNEEKNEEEISLEDLIETERSLLGANVTRITLETF 257

  Fly   246 LAWKKRKIAEKKAKLAAEEERKKSDFSKGKQFGISGREMFSFNPDLVDDGPME-------EGDAA 303
            |||||||..||.||...:.||||:||..|:..|:||||:|.|.|:||||...|       |.|..
Zfish   258 LAWKKRKRQEKLAKAEQDMERKKADFKAGRALGVSGREVFEFRPELVDDDDEEADDTKYAEEDYN 322

  Fly   304 FDVYNREDDDDNAVEFKELDLAALSLAAKEVDGSG-TIAS----------TNRLLDQATEAAKTA 357
            :.:.|:.:|.:   |.:::|:|  ....||||.:| |:||          ||.:.|.....|...
Zfish   323 YGMSNQVEDTE---EVQDIDIA--RFIPKEVDNAGITVASADRFTAKAPPTNDIDDNKLSEASGG 382

  Fly   358 AAEDAAADEDGPSSSAPAN---DAAPINKDLFV-----DLAGELDDLDLDD 400
            ..|:....||........|   :|.|::::||.     :|..||:.||||:
Zfish   383 TMENGEHSEDQTLEDGETNEESEAVPVDENLFTGEDLDELEEELNTLDLDE 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8635	NP_610401.1	COG5252	1..314	CDD:227577	198/334 (59%)
zc3h15	NP_956182.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		11/18 (61%)
		COG5252	28..321	CDD:227577	176/295 (60%)
		Required for interaction with DRG1. /evidence=ECO:0000250	238..262		16/23 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	358..420		12/61 (20%)